kaempferol 3-O-(2''-O-β-D-glucopyranosyl)-α-L-rhamnopyranoside-nonaacetate | 144049-88-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: kaempferol 3-O-(2''-O-β-D-glucopyranosyl)-α-L-rhamnopyranoside-nonaacetate
• CAS: 144049-88-7
• 化学式: C₄₅H₄₈O₂₄
• 分子量: 972.862
• InChiKey: OCGLRVUPEPSXSQ-AJBXWGEBSA-N

反应信息

• 作为产物：
  描述：

  乙酸酐 、 3-[(2S,3R,4R,5R,6S)-4,5-二羟基-6-甲基-3-[(2S,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟基甲基)四氢吡喃-2-基]氧基四氢吡喃-2-基]氧基-5,7-二羟基-2-(4-羟基苯基)苯并吡喃-4-酮 在 吡啶 作用下， 生成 kaempferol 3-O-(2''-O-β-D-glucopyranosyl)-α-L-rhamnopyranoside-nonaacetate
  参考文献：
  名称：

  Selective Responses of Three Ginkgo biloba Leaf-Derived Constituents on Human Intestinal Bacteria

  摘要：

  The selective responses of Ginkgo biloba leaf-derived materials against six intestinal bacteria was examined using an impregnated paper disk method and compared with that of bilobalide, ginkgolides A and B, kaempferol, and quercetin. The components of G. biloba leaves were characterized as kaempferol 3-O-alpha-(6'''-p-coumaroylglucosyl-beta-1,4-rhamnoside), kaempferol 3-O-(2"-O-D-glucopyranosyl)-alpha-L-rhamnopyranoside, and quercetin 3-O-alpha-(6'''-p-coumaroylglucosyl-beta-1,4-rhamnoside) by spectroscopic analysis. The growth responses varied with each bacterial strain tested. At 2 mg/disk, kaempferol 3-O-alpha-(6'''-p-coumaroylglucosyl-beta-1,4-rhamnoside) and quercetin 3-O-alpha-(6'''-p-coumaroylglucosyl-beta-1,4-rhamnoside) revealed potent inhibition against Clostridium perfringens, and kaempferol 3-O-(2"-O-beta-D-glucopyranosyl)-alpha-L-rhamnopyranoside showed a clear inhibitory effect on Escherichia coli. At 0.5 mg/disk, quercetin 3-O-alpha-(6'''-p-coumaroylglucosyl-beta-1,4-rhamnoside) showed a strong activity against C. perfringens, but weak activity was exhibited by kaempferol 3-O-alpha-(6'''-p-coumaroylglucosyl-beta-1,4-rhamnoside) against C. perfringens and kaempferol 3-O-(2"-O-beta-D-glucopyranosyl)-alpha-L-rhamnopyranoside against E coli. No inhibition was observed from treatments conducted with bilobalide, ginkgolides A and B, kaempferol, or quercetin. Furthermore, these isolated compounds did not inhibit Bifidobacterium bifidum, B. longum, B. adolescentis, or Lactobacillus acidophilus.

  DOI：

  10.1021/jf011140a