2,2-Heptamethylen-1,3-dioxandion-(4,6) | 99861-80-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,2-Heptamethylen-1,3-dioxandion-(4,6)
• 英文别名: 1,5-dioxa-spiro[5.7]tridecane-2,4-dione；1,5-Dioxaspiro[5.7]tridecane-2,4-dione
• CAS: 99861-80-0
• 化学式: C₁₁H₁₆O₄
• 分子量: 212.246
• InChiKey: HGHMRKHTZMGXAG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Method of fluorination using iodonium ylides
  申请人：The General Hospital Corporation

  公开号：US10259800B2

  公开（公告）日：2019-04-16

  A process for fluorination of aromatic compounds employing iodonium ylides and applicable to radiofluorination using 18F is described. Processes, intermediates, reagents and radiolabelled compounds are described.

  描述了一种使用碘化亚烯并适用于使用18F进行放射性氟化的芳香化合物氟化的过程。描述了过程、中间体、试剂和标记化合物。
• Method for Producing 1,3-Dioxolan-4,6-Dione Compound
  申请人：Sato Shingo

  公开号：US20080015365A1

  公开（公告）日：2008-01-17

  A method for producing a 1,3-dioxolan-4,6-dione compound from a ketone compound and a malonic acid, the method comprising: precipitating a 1,3-dioxolan-4,6-dione compound as a crystal from a mixed solvent comprising a first organic solvent having a dielectric constant of 10 or more and a water, so as to form a precipitated 1,3-dioxolan-4,6-dione compound; and isolating the precipitated 1,3-dioxolan-4,6-dione compound by a solid-liquid separation.
• METHOD OF FLUORINATION USING IODONIUM YLIDES
  申请人：The General Hospital Corporation

  公开号：US20170121300A1

  公开（公告）日：2017-05-04

  A process for fluorination of aromatic compounds employing iodonium ylides and applicable to radiofluorination using 18 F is described. Processes, intermediates, reagents and radiolabelled compounds are described.
• US7442809B2
  申请人：——

  公开号：US7442809B2

  公开（公告）日：2008-10-28