(2S,3S,4S,5R,6S)-3-((2S,4aR,6S,7R,8R,8aR)-7-Azido-8-hydroxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-6-(4-methoxy-phenoxy)-4,5-bis-(4-methyl-benzoyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester | 180274-61-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3S,4S,5R,6S)-3-((2S,4aR,6S,7R,8R,8aR)-7-Azido-8-hydroxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-6-(4-methoxy-phenoxy)-4,5-bis-(4-methyl-benzoyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester
• CAS: 180274-61-7
• 化学式: C₄₃H₄₃N₃O₁₄
• 分子量: 825.826
• InChiKey: CREROONRPZZWQJ-FCGMBJPYSA-N

反应信息

• 作为反应物：
  描述：

  (2S,3S,4S,5R,6S)-3-((2S,4aR,6S,7R,8R,8aR)-7-Azido-8-hydroxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-6-(4-methoxy-phenoxy)-4,5-bis-(4-methyl-benzoyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester 、 (2S,3S,4S,5R,6R)-3-[(2S,4aR,6S,7R,8R,8aR)-7-Azido-8-(4-oxo-pentanoyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy]-4,5-bis-(4-methyl-benzoyloxy)-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester 在 4 A molecular sieve 、 三氟化硼乙醚 作用下， 以 甲苯 为溶剂， 以50%的产率得到Methyl 4)-O-(methyl 2,3-di-O-p-methylbenzoyl-β-D-glucopyranosyluronate)-(1->3)-O-(2-azido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranosyl)-(1->4)-...
  参考文献：
  名称：

  Tamura, Jun-Ichi; Neumann, Klaus W.; Ogawa, Tomoya, Liebigs Annalen, 1996, # 8, p. 1239 - 1257

  摘要：

  DOI：
• 作为产物：
  描述：

  (2S,3S,4S,5R,6S)-3-[(2S,4aR,6S,7R,8R,8aR)-7-Azido-8-(4-oxo-pentanoyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy]-6-(4-methoxy-phenoxy)-4,5-bis-(4-methyl-benzoyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester 在 乙酸肼 作用下， 以 乙醇 、 甲苯 为溶剂， 生成 (2S,3S,4S,5R,6S)-3-((2S,4aR,6S,7R,8R,8aR)-7-Azido-8-hydroxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-6-(4-methoxy-phenoxy)-4,5-bis-(4-methyl-benzoyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester
  参考文献：
  名称：

  Tamura, Jun-Ichi; Neumann, Klaus W.; Ogawa, Tomoya, Liebigs Annalen, 1996, # 8, p. 1239 - 1257

  摘要：

  DOI：

文献信息

• Synthesis of chondroitin sulfate E octasaccharide in a repeating region involving an acetamide auxiliary
  作者：Jun-ichi Tamura、Yuka Nakada、Kayo Taniguchi、Manami Yamane

  DOI：10.1016/j.carres.2007.09.009

  日期：2008.1

  Chondroitin sulfate E repeating octasaccharide was effectively synthesized in a stereocontrolled manner by adopting an acetamide-type disaccharide unit. In the tetrasaccharide synthesis we isolated a characteristic glycosyl imidate as a reactive intermediate. An acetamide auxiliary involves the glycosylation mechanism. (c) 2007 Elsevier Ltd. All rights reserved.