(11E,21E)-Dotriaconta-11,21-dienedioic acid dimethyl ester | 182141-18-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (11E,21E)-Dotriaconta-11,21-dienedioic acid dimethyl ester
• CAS: 182141-18-0
• 化学式: C₃₄H₆₂O₄
• 分子量: 534.864
• InChiKey: OKLJPDHRULASPJ-UHFFFAOYSA-N

物化性质

• 沸点：
  582.4±23.0 °C(predicted)
• 密度：
  0.915±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  10.59
• 重原子数：
  38.0
• 可旋转键数：
  29.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  52.6
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  (11E,21E)-Dotriaconta-11,21-dienedioic acid dimethyl ester 在 铂 氢气 作用下， 以 1,4-二氧六环 为溶剂， 以56%的产率得到dotriacontanedioic acid dimethyl ester
  参考文献：
  名称：

  Synthesis of new bifluorophoric probes adapted to studies of donor-donor electronic energy transfer in lipid systems

  摘要：

  A series of bifluorophoric fluorescent probes with identical pairs of chromophores have been synthesized. The fluorophores are 9-anthryl, 3-perylenyl and rhodamine 101, and they are separated by a long rigid (bisteroid) or flexible (dotriacontane) diol spacer. The probes are designed for studies of intra- and intermolecular electronic energy transfer in lipid systems such as model and biological membranes. They are shown to incorporate in phosphatidylcholine vesicles with an hitherto unknown orientation.

  DOI：

  10.1016/0009-3084(96)02537-6
• 作为产物：
  描述：

  methyl 11-iodoundecanoate 在 十二/十四烷基二甲基氧化胺 、 potassium 2-methylbutan-2-olate 作用下， 以 氯仿 为溶剂， 反应 1.25h， 生成 (11E,21E)-Dotriaconta-11,21-dienedioic acid dimethyl ester
  参考文献：
  名称：

  Synthesis of new bifluorophoric probes adapted to studies of donor-donor electronic energy transfer in lipid systems

  摘要：

  A series of bifluorophoric fluorescent probes with identical pairs of chromophores have been synthesized. The fluorophores are 9-anthryl, 3-perylenyl and rhodamine 101, and they are separated by a long rigid (bisteroid) or flexible (dotriacontane) diol spacer. The probes are designed for studies of intra- and intermolecular electronic energy transfer in lipid systems such as model and biological membranes. They are shown to incorporate in phosphatidylcholine vesicles with an hitherto unknown orientation.

  DOI：

  10.1016/0009-3084(96)02537-6