[p-(trifluoroacetamido)phenyl]ethyl 3-O-(β-D-glucopyranosyl)-4-O-(β-D-glucopyranosyl)-6-O-(3,4,6-tri-O-benzyl-2-O-{α-D-glucopyranosyl}-β-D-glucopyranosyl)-α-D-glucopyranoside | 1352615-16-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [p-(trifluoroacetamido)phenyl]ethyl 3-O-(β-D-glucopyranosyl)-4-O-(β-D-glucopyranosyl)-6-O-(3,4,6-tri-O-benzyl-2-O-{α-D-glucopyranosyl}-β-D-glucopyranosyl)-α-D-glucopyranoside
• CAS: 1352615-16-7
• 化学式: C₄₀H₆₀F₃NO₂₇
• 分子量: 1043.9
• InChiKey: XNKVYMWRUPUUEK-LMBVMHBQSA-N

反应信息

• 作为产物：
  描述：

  在 甲醇 、 sodium 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以8.5 mg的产率得到[p-(trifluoroacetamido)phenyl]ethyl 3-O-(β-D-glucopyranosyl)-4-O-(β-D-glucopyranosyl)-6-O-(3,4,6-tri-O-benzyl-2-O-{α-D-glucopyranosyl}-β-D-glucopyranosyl)-α-D-glucopyranoside
  参考文献：
  名称：

  Synthesis of a novel pentasaccharide core component from the lipooligosaccharide of Moraxella catarrhalis

  摘要：

  The novel pentasaccharide [p-(trifluoroacetamido)phenyl]ethyl 3-O-beta-D-glucopyranosyl-4-O-beta-D-glucopyranosyl-6-O-[2-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranosyl]-alpha-D-glucopyranoside (1), which includes a linker moiety to enable facile coupling to an antigenic protein, was synthesised as a component of a potential vaccine candidate against the Gram-negative bacterium Moraxella catarrhalis. This microorganism is one of three principal causative agents of otitis media in children. The pentasaccharide represents a common cross-serotype (A, B and C) structure from the lipooligosaccharides of Moraxella catarrhalis. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2011.10.002