4-核糖基氨基-2,5-二氨基-6-羟基嘧啶 | 27248-39-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 4-核糖基氨基-2,5-二氨基-6-羟基嘧啶
• 英文名称: 4-Ribitylamino-2,5-diamino-6-hydroxypyrimidine
• 英文别名: 2,5-diamino-4-[[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]amino]-1H-pyrimidin-6-one
• CAS: 27248-39-1
• 化学式: C₉H₁₇N₅O₅
• 分子量: 275.26
• InChiKey: FCJPQLSIAKACJT-RPDRRWSUSA-N

物化性质

• 沸点：
  728.2±70.0 °C(Predicted)
• 密度：
  1.92±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -3.6
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  186
• 氢给体数：
  8
• 氢受体数：
  7

文献信息

• Transformation systems for flavinogenic yeast
  申请人：——

  公开号：US20030082815A1

  公开（公告）日：2003-05-01

  This invention is directed to the transformation of the flavinogenic yeasts, Pichia guilliermondii and Candida famata , and mutants thereof, by electroporation (electrotransformation) and by spheroplast transformation. The invention is also directed to nucleic acid constructs such as vectors, plasmids, and ARS sequences which transform flavinogenic yeasts, and mutants thereof, at a high level and in a stable manner so as to result in stably transformed yeast host cells which express/produce recombinant products. This invention also is directed to flavinogenic yeasts, Pichia guilliermondii and Candida famata , and mutants and temperature sensitive mutants thereof, which produce or overproduce riboflavin.

  本发明针对黄素酵母的转化、 Pichia guilliermondii 和 念珠菌 及其突变体。本发明还涉及核酸构建体，如载体、质粒和 ARS 序列，它们能以高水平和稳定的方式转化黄素酵母及其突变体，从而产生稳定转化的酵母宿主细胞，表达/产生重组产物。本发明还针对黄素酵母、 Pichia guilliermondii 和 念珠菌 及其产生或过量产生核黄素的突变体和对温度敏感的突变体。
• TRANSFORMATION SYSTEMS FOR FLAVINOGENIC YEAST
  申请人：ARCHER-DANIELS-MIDLAND COMPANY

  公开号：EP1332207B1

  公开（公告）日：2008-10-29
• COMPLETE GENOME SEQUENCE OF THE METHANOGEN METHANOBREVIBACTER RUMINANTIUM
  申请人：Pastoral Greenhouse Gas Research Ltd

  公开号：EP2470660A1

  公开（公告）日：2012-07-04
• US7009045B2
  申请人：——

  公开号：US7009045B2

  公开（公告）日：2006-03-07
• [EN] TRANSFORMATION SYSTEMS FOR FLAVINOGENIC YEAST<br/>[FR] SYSTÈMES DE TRANSFORMATION POUR LEVURE FLAVINOGÈNE
  申请人：ABBAS CHARLES

  公开号：WO2002006448A2

  公开（公告）日：2002-01-24

  This invention is directed to the transformation of the flavinogenic yeasts, Pichia guilliermondii and Candida famata, and mutants therof, by electroporation (electrotransformation) and by spheroplast transformation. The invention is also directed to nucleic acid constructs such as vectors, plasmids, and ARS sequences which transform flavinogenic yeasts, and mutants thereof, at a high level and in a stable manner so as to result in stably transformed yeast host cells which express/produce recombinant products. This invention also is directed to flavinogenic yeasts, Pichia guilliermondii and Candida famata, and mutants and temperature sensitive mutants thereof, which produce or overproduce riboflavin.