1-phenyl-3-(pyridin-2-ylmethylimino)butan-1-one | 402500-34-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-phenyl-3-(pyridin-2-ylmethylimino)butan-1-one
• CAS: 402500-34-9
• 化学式: C₁₆H₁₆N₂O
• 分子量: 252.316
• InChiKey: XARXXGPXMYBWCY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  42.3
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-氨甲基吡啶 、 1-苯基-1,3-丁二酮 以 甲醇 为溶剂， 反应 2.0h， 生成 1-phenyl-3-(pyridin-2-ylmethylimino)butan-1-one
  参考文献：
  名称：

  Effect of ligand substitution on DNA binding ability of two new square planar copper(II)–Schiff base complexes

  摘要：

  Two terdentate NNO donor Schiff base ligands CH3C(OH=CHC(CH3)=NCH2C5H4N [HL1] and C6H5C(OH)=CHC(CH3)=NCH2C5H4N [HL2] were used to synthesize two mononuclear square planar copper(II) complexes, [CuL1(CF3COO)] (1) and [CuL2(CF3COO)] (2). The complexes were characterized by elemental analyses, FT-IR, UV-vis spectral methods and their structures were established by single crystal X-ray diffraction study. The biochemical activity of the complexes towards DNA binding were performed using absorbance and fluorescence titration methods and their mode of binding with calf thymus DNA has been established by viscosity measurement technique. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molstruc.2010.04.034