2-[(E)-2-(2-methoxyphenyl)ethenyl]-1,3-dithiolane | 116972-95-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-[(E)-2-(2-methoxyphenyl)ethenyl]-1,3-dithiolane
• CAS: 116972-95-3
• 化学式: C₁₂H₁₄OS₂
• 分子量: 238.375
• InChiKey: PEWHOZPFKJFFOW-VOTSOKGWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  59.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  magnesium,methanidyl-dimethyl-propan-2-yloxysilane,chloride 、 2-[(E)-2-(2-methoxyphenyl)ethenyl]-1,3-dithiolane 在 bis(triphenylphosphine)nickel(II) chloride 作用下， 以 四氢呋喃 为溶剂， 反应 16.0h， 以88%的产率得到Isopropoxy-[(1E,3E)-4-(2-methoxy-phenyl)-buta-1,3-dienyl]-dimethyl-silane
  参考文献：
  名称：

  Novel Synthesis of Dienylsiloxanes. Stereoselective Synthesis of 3-Cyclohexene-1,2-diols by Intramolecular Diels-Alder Reactions of Siloxane-Tethered Bis-Dienes

  摘要：

  DOI：

  10.1021/jo00116a004

文献信息

• Ni, Zhi-Jie; Yang, Pin-Fan; Ng, Dennis K. P., Journal of the American Chemical Society, 1990, vol. 112, # 25, p. 9356 - 9364
  作者：Ni, Zhi-Jie、Yang, Pin-Fan、Ng, Dennis K. P.、Tzeng, Yih-Ling、Luh, Tien-Yau

  DOI：——

  日期：——
• Transition-metal-promoted reactions. 25. Regioselective silylolefination of allylic dithioacetals. Stereoselective synthesis of 1-(trimethylsilyl)butadienes
  作者：Zhi Jie Ni、Tien Yau Luh

  DOI：10.1021/jo00258a047

  日期：1988.11
• Transition metal promoted reactions. 38. NiCl2(dppe)-catalyzed geminal dialkylation of dithioacetals and trimethylation of ortho thioesters
  作者：Yih Ling Tzeng、Ping Fan Yang、Nai Wen Mei、Tien Min Yuan、Chun Chi Yu、Tien Yau Luh

  DOI：10.1021/jo00018a016

  日期：1991.8

  NiCl2(dppe)-catalyzed cross-coupling of cinnamaldehyde dithioacetals gave the corresponding geminal dimethylation products in excellent yields. Allylic ortho thioesters afforded regioselectively the corresponding trimethylation products. The reaction may occur via an 18-electron pi-allyl intermediate, which undergoes facile reductive elimination to afford the geminal dimethylation product. Benzylic dithioacetals having an ortho amino group gave 2-isopropylanilines exclusively. The reaction of benzylic dithioacetals with EtMgBr under the same conditions yielded geminal diethylation products.
• Transition metal promoted reaction. 26. Nickel catalyzed geminal dimethylation of allylic dithioacetals
  作者：Ping Fan Yang、Zhi Jie Ni、Tien Yau Luh

  DOI：10.1021/jo00271a001

  日期：1989.5
• JANG, PING-FAN;NI, ZHI-JIE;LUH, TIEN-JAU, J. ORG. CHEM., 54,(1989) N0, C. 2261-2263
  作者：JANG, PING-FAN、NI, ZHI-JIE、LUH, TIEN-JAU

  DOI：——

  日期：——