[(R)-1,1'-bi-2-naphtholato]bis(2-adamantyloxo)titanium(IV) | 913342-79-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯氮卓类
• 英文名称: [(R)-1,1'-bi-2-naphtholato]bis(2-adamantyloxo)titanium(IV)
• CAS: 913342-79-7
• 化学式: C₄₀H₄₂O₄Ti
• 分子量: 634.651
• InChiKey: ZLOOCXJTDXPMLA-ILANIMGWSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  [(R)-1,1'-bi-2-naphtholato]bis(2-adamantyloxo)titanium(IV) 、 水 以 乙醚 、 甲苯 为溶剂， 生成 Ti4[(R)-μ-1,1'-bi-2-naphtholato]4(2-adamantyloxo)4(μ3-O)2
  参考文献：
  名称：

  Modification of alkoxo ligands of BINOL–Ti ladder: Isolation and X-ray crystallographic analysis

  摘要：

  The stable binaphthol-titanium ladder complexes have been successfully prepared by using bulky alkoxo ligands. From the secondary OR ligand (cyclohexyloxo, 2,4-dimethyl-3-pentyloxo or 2-adamantyloxo) and terially OR ligand (tert-butyloxo, 1-adamantyloxo), partial hydrolysis proceeded to give the mu(3)-oxo titanium complexes. The use of [Ti(BINOLato)(OEt)(2)](n), made it possible to prepare the Ti(BINOLato)(OR)2 complexes using alcohols (ROH) of high boiling point (R = cyclohexyl, 2-adamantyl, 1-adamantyl). X-ray analyses of [(R)-1, 1'-bi-2-naphtholato]bis(O-2,4-dimethyl-3-pentyloxo)titanium and [(R)-3,3'-dimethyl-naphtholato]bis(2-adamant- yloxo)titanium showed a good agreement with the estimated ladder complexes. The catalytic activity of BINOL-Ti catalyst analogues, obtained by partial hydrolysis of Ti(BINOLato)(OR)(2) with wet MS 4A was studied in asymmetric glyoxylate-ene reaction by two methods. Moderate to good chemical yields and enantioselectivities were obtained. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2005.11.052
• 作为产物：
  描述：

  S-1,1'-联-2-萘酚 、 2-金刚烷醇 、 titanium(IV) tetraethanolate 以 甲苯 为溶剂， 以82%的产率得到[(R)-1,1'-bi-2-naphtholato]bis(2-adamantyloxo)titanium(IV)
  参考文献：
  名称：

  Modification of alkoxo ligands of BINOL–Ti ladder: Isolation and X-ray crystallographic analysis

  摘要：

  The stable binaphthol-titanium ladder complexes have been successfully prepared by using bulky alkoxo ligands. From the secondary OR ligand (cyclohexyloxo, 2,4-dimethyl-3-pentyloxo or 2-adamantyloxo) and terially OR ligand (tert-butyloxo, 1-adamantyloxo), partial hydrolysis proceeded to give the mu(3)-oxo titanium complexes. The use of [Ti(BINOLato)(OEt)(2)](n), made it possible to prepare the Ti(BINOLato)(OR)2 complexes using alcohols (ROH) of high boiling point (R = cyclohexyl, 2-adamantyl, 1-adamantyl). X-ray analyses of [(R)-1, 1'-bi-2-naphtholato]bis(O-2,4-dimethyl-3-pentyloxo)titanium and [(R)-3,3'-dimethyl-naphtholato]bis(2-adamant- yloxo)titanium showed a good agreement with the estimated ladder complexes. The catalytic activity of BINOL-Ti catalyst analogues, obtained by partial hydrolysis of Ti(BINOLato)(OR)(2) with wet MS 4A was studied in asymmetric glyoxylate-ene reaction by two methods. Moderate to good chemical yields and enantioselectivities were obtained. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2005.11.052