The intramolecular silyl modified sakurai (ISMS) reaction. A novel and highly convergent synthesis of oxocenes
作者:Abdelaziz Mekhalfia、István E Markó、Harry Adams
DOI:10.1016/s0040-4039(00)92307-4
日期:1991.1
By employing the intramolecular version of the SMS reaction, oxocenes, including spiroethers and spiroketals, can be prepared in a highly convergent, one-step operation.
通过使用SMS的分子内形式,可以以高度收敛的一步式操作制备茂新化合物,包括螺醚和螺酮化合物。
Novel mercuric triflate-catalyzed condensation of ketones and homoallyl alcohols
Novel condensation of ketones with homoallyl alcohols catalyzed by Hg(OTf)2 has been developed, generating a 6-membered ring ether alcohol, bisether, and olefins. The reaction is initiated b hemiacetal formation, and cyclization of the resulting oxonium cation provides the 6-membered ring carbocation as a common intermediate. Thus, it is a catalytic Prins-type condensation of non-activated homoallyl
A novel odorant of formula (I) wherein each of R
1
, R
2
, R
3
, R
4
, R
5
, R
6
, R
7
, R
8
, R
9
and R
10
are independently selected from H, CH
3
, and C
2
H
5
; X is selected from —CH
2
OH, —CH
2
OCOCH
3
and —CHO and —CHO, n is selected from 0 and 1. The dotted line represents double bond or single bond.
A novel odorant of formula (I) wherein each of R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are independently selected from H, CH3, and C2H5; X is selected from —CH2OH, —CH2OCOCH3 and —CHO and —CHO, n is selected from 0 and 1. The dotted line represents double bond or single bond.