1-(2-bromo-4-cyclohexylphenyl)ethanone | 1376626-96-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(2-bromo-4-cyclohexylphenyl)ethanone
• CAS: 1376626-96-8
• 化学式: C₁₄H₁₇BrO
• 分子量: 281.192
• InChiKey: UAKPOKYAFVHNDT-UHFFFAOYSA-N

物化性质

• 沸点：
  368.9±42.0 °C(Predicted)
• 密度：
  1.287±0.06 g/cm3(Predicted)

反应信息

• 作为反应物：
  描述：

  1-(2-bromo-4-cyclohexylphenyl)ethanone 在 stems and germinated seed of Brassica oleracea variety italica 作用下， 以 水 为溶剂， 反应 48.0h， 以47%的产率得到(S)-1-(2-bromo-4-cyclohexylphenyl)ethanol
  参考文献：
  名称：

  Highly enantioselective bioreduction of prochiral ketones by stem and germinated plant ofBrassica oleraceavarietyitalica

  摘要：

  An eco-friendly and environmentally benign asymmetric reduction of a broad range of prochiral ketones employing Brassica oleracea variety italica (stems and germinated plant) as a novel biocatalyst was developed. It was found that B. oleracea variety italica could be used effectively for enantioselective bioreduction in aqueous medium with moderate to excellent chemical yield and enantiomeric excess (ee). This process is more efficient and generates less waste than conventional chemical reagents or microorganisms. Both R- and S-configurations were obtained by these asymmetric reactions. The best ee were achieved for pyridine derivatives (92-99%). The ee in germinated plant reactions were significantly higher than those of stem reactions. The low cost and the easy availability of these biocatalysts suggest their possible use for large scale preparations of important chiral alcohols.

  DOI：

  10.3109/10242422.2011.635302