benzyl {3-[4-(5-isopropoxypyridin-2-yloxy)phenyl]-1-methylpropyl}carbamate | 1204483-06-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: benzyl {3-[4-(5-isopropoxypyridin-2-yloxy)phenyl]-1-methylpropyl}carbamate
• 英文别名: benzyl N-[4-[4-(5-propan-2-yloxypyridin-2-yl)oxyphenyl]butan-2-yl]carbamate
• CAS: 1204483-06-6
• 化学式: C₂₆H₃₀N₂O₄
• 分子量: 434.535
• InChiKey: GOXORPLRMPNSDH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  32
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  69.7
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• US8470841B2
  申请人：——

  公开号：US8470841B2

  公开（公告）日：2013-06-25
• [EN] HETEROCYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THE USE THEREOF<br/>[FR] COMPOSÉS HÉTÉROCYCLIQUES, LEURS PROCÉDÉS DE PRÉPARATION, MÉDICAMENTS COMPRENANT LESDITS COMPOSÉS ET LEUR UTILISATION
  申请人：SANOFI AVENTIS

  公开号：WO2010003624A2

  公开（公告）日：2010-01-14

  Heterocyclic derivatives, processes for their preparation, medicaments comprising these compounds, and the use thereof. The invention relates to compounds of the formula I in which the radicals R1, R2, R3, R4, W, A, B, D, E, G, L, M, R, T and Y have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example for the treatment of the metabolic syndrome, insulin resistance, obesity and diabetes.