N-ethyl-3-hydroxybutanamide | 89584-18-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-ethyl-3-hydroxybutanamide
• CAS: 89584-18-9
• 化学式: C₆H₁₃NO₂
• mdl: MFCD19222559
• 分子量: 131.17
• InChiKey: GSIPBDZNJDVUEQ-UHFFFAOYSA-N

物化性质

• 沸点：
  92 °C(Press: 0.1 Torr)
• 密度：
  0.998±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.833
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Method for preparing optically active beta-butyrolactones
  申请人：Watanabe Shinya

  公开号：US20060046286A1

  公开（公告）日：2006-03-02

  The present invention is to provide a method for preparing easily and efficiently β-butyrolactones and/or optically active 3-hydroxycarboxylic acid derivatives in high optical purity by use of an easily available hydrolase, which are useful as intermediates for pharmaceuticals, agrochemicals and the like. More particularly, the present invention relates to a method for preparing β-butyrolactones and/or optically active 3-hydroxycarboxylic acid derivatives with an optical purity of substantially 100% ee, comprising reacting a β-butyrolactone which is a mixture of optical isomers, with a nucleophilic agent in the presence of a hydrolase, provided that a lipase derived from porcine pancreas is excluded.

  本发明提供了一种使用易得的水解酶高效制备β-丁内酯和/或高光学纯度的光学活性3-羟基羧酸衍生物的方法，这些衍生物作为制药、农药等中间体具有应用价值。更具体地说，本发明涉及一种制备β-丁内酯和/或光学活性3-羟基羧酸衍生物的方法，其光学纯度达到实质上100% ee，包括在水解酶的存在下，用亲核试剂反应混合光学异构体的β-丁内酯，但不包括来自猪胰脂肪酶的酶。
• Novel lipopeptides as antibacterial agents
  申请人：Hill Jason

  公开号：US20050203006A1

  公开（公告）日：2005-09-15

  The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.

  本发明涉及新型脂肽化合物。本发明还涉及这些化合物的药物组合物以及将这些化合物用作抗菌化合物的方法。本发明还涉及生产这些新型脂肽化合物和用于生产这些化合物的中间体的方法。
• METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS
  申请人：Biocatalytics, Inc.

  公开号：EP0991772A1

  公开（公告）日：2000-04-12
• US5834261A
  申请人：——

  公开号：US5834261A

  公开（公告）日：1998-11-10
• US5942644A
  申请人：——

  公开号：US5942644A

  公开（公告）日：1999-08-24