6-O-octanoyl-α-D-glucose | 143823-61-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-O-octanoyl-α-D-glucose
• 英文别名: 6-O-capryloylglucose；[(2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl] octanoate
• CAS: 143823-61-4
• 化学式: C₁₄H₂₆O₇
• 分子量: 306.356
• InChiKey: HEGOZZGDTGYRGM-OIMNJJJWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  21
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  124
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• Non-yellowing topical pharmaceutical composition
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0052404A2

  公开（公告）日：1982-05-26

  Topical compositions, containing tetracycline, tetracycline salts or tetracycline derivatives, which do not cause skin yellowing, are disclosed. These compositions are formulated such that, upon application to the skin, the tetracycline component recrystallizes in small, irregular crystals at the skin surface. Preferred compositions are buffered at a pH between about 2.0 and 4, such as by the addition of citric acid. The method of treating skin disorders such as acne, using these compositions is also disclosed.

  本发明公开了含有四环素、四环素盐或四环素衍生物的外用组合物，这些组合物不会导致皮肤变黄。这些组合物的配制方式是，在涂抹到皮肤上后，四环素成分在皮肤表面重结晶成不规则的小晶体。优选组合物的 pH 值在 2.0 至 4 之间，如加入柠檬酸。此外，还公开了使用这些组合物治疗痤疮等皮肤疾病的方法。
• Bleaching detergent composition
  申请人：NOVO NORDISK A/S

  公开号：EP0380437A2

  公开（公告）日：1990-08-01

  Esters of monosaccharides and their lower alkyl glycosides are effective both as surfactants and as bleach activators (peracid precursors). The compounds are non-toxic and biodegradable. They act as nonionic surfactants and are effective in soil removal from textiles, e.g. of fatty soiling. In the presence of a hydrogen peroxide source, the sugar derivatives are perhydrolyzed during the washing process to form long-chain peracid. This enhances the bleaching effect, especially on hydrophobic stains.

  单糖酯及其低级烷基糖苷既可用作表面活性剂，也可用作漂白剂活化剂（过酸前体）。这些化合物无毒，可生物降解。它们可作为非离子表面活性剂，有效清除纺织品上的污垢，如脂肪污垢。在有过氧化氢源的情况下，糖衍生物会在洗涤过程中发生过水解，形成长链过酸。这就增强了漂白效果，尤其是对疏水性污渍的漂白效果。
• Process for producing saccharide fatty acid monoesters
  申请人：LION CORPORATION

  公开号：EP0413307A1

  公开（公告）日：1991-02-20

  A process for producing a saccharide fatty acid monoester comprises reacting an immobilized thermostable lipase on a mixture comprising: (A) one or more of acyl donors selected from saturated and unsaturated fatty acids with 6 to 22 carbon atoms, lower alkyl esters of said fatty acids and glycerol esters of said fatty acids, (B) one or more of saccharides selected from monosaccharides with 5 to 7 carbon atoms, disaccharides composed of hexose, sugar alcohols with 4 to 6 carbon atoms, ethers of monosaccharides with 5 to 7 carbon atoms and monohydric alcohols and ethers of disaccharides composed of hexose and monohydric alcohols, and (C) one or more of alcohols selected from secondary alcohols and tertiary alcohols.

  一种生产糖类脂肪酸单酯的工艺包括将固定化的恒温脂肪酶与一种混合物反应，该混合物包括 (A) 一种或多种选自具有 6 至 22 个碳原子的饱和和不饱和脂肪酸、所述脂肪酸的低级烷基酯和所述脂肪酸的甘油酯的酰基供体、 (B) 一种或多种选自 5 至 7 个碳原子的单糖、由己糖组成的二糖、4 至 6 个碳原子的糖醇、5 至 7 个碳原子的单糖和一元醇的醚以及由己糖和一元醇组成的二糖的醚的糖类，以及 (C) 选自仲醇和叔醇的一种或多种醇。
• Nonionic surface active agent
  申请人：LION CORPORATION

  公开号：EP0427210A2

  公开（公告）日：1991-05-15

  A nonionic surface active agent comprising a fatty acid ester of a hexose sugar or an alkyl glycoside thereof, wherein the content of monoester is from 93 to 99.9% by weight, the content of diester is from 0.1 to 7% by weight and the content of tri- and higher polyesters is from 0 to 1% by weight in the fatty acid ester.

  一种非离子表面活性剂，包括六糖脂肪酸酯或其烷基糖苷，其中单酯的含量为 93% 至 99.9%（按重量计），二酯的含量为 0.1% 至 7%（按重量计），三酯及以上聚酯的含量为 0% 至 1%（按重量计）。
• Enantiomerically-enhanced nutritional energy substrates
  申请人：CLINTEC NUTRITION COMPANY

  公开号：EP0736256A1

  公开（公告）日：1996-10-09

  The present disclosure generally relates to the field of enteral and parenteral nutritional formulations in which enantiomerically-enriched energy substrates are used for providing high caloric density and low osmolarity. In particular monoisomeric glyceryl tri(chiral alkanoates), anomeric mixtures of alpha, beta-D-glucopyranosyl alkanoates, monoisomeric chiral alkanoic acid esters, anomeric chiral alkanoic acid esters as well as methods for their preparation and their use in enteral or parenteral nutrition, for metabolic disorder, trauma and malnutrition are described.

  本公开内容一般涉及肠内和肠外营养制剂领域，其中对映体富集的能量底物用于提供高热量密度和低渗透压。特别是描述了单异构体甘油三（手性烷酸酯）、α、β-D-吡喃葡萄糖基烷酸酯的异构体混合物、单异构体手性烷酸酯、异构体手性烷酸酯以及它们的制备方法和在肠内或肠外营养中的用途，用于代谢紊乱、创伤和营养不良。