3-formyl-α-L-5-deoxy-lyxofuranose | 37111-65-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-formyl-α-L-5-deoxy-lyxofuranose
• 英文别名: (2S,3S,4R,5R)-3,4,5-trihydroxy-2-methyloxolane-3-carbaldehyde
• CAS: 37111-65-2
• 化学式: C₆H₁₀O₅
• 分子量: 162.142
• InChiKey: PSLNNVPHIJQGRF-UNTFVMJOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Directed evolution of biosynthetic and biodegradation pathways
  申请人：CALIFORNIA INSTITUTE OF TECHNOLOGY

  公开号：US20020051998A1

  公开（公告）日：2002-05-02

  The present invention relates to engineering new biosynthetic pathways into microorganisms, in particular biosynthetic carotenoid pathways. New and improved catalytic functions of metabolic pathways are created by, for example, site-specific mutation or gene shuffling techniques, to provide for efficient biosynthesis of carotenoids. By applying the described directed evolution techniques, almost any carotenoid could be produced, in a host cell, from one or a few sets of genes. In addition, the described techniques are useful for creating gene or protein libraries for new and uncharacterized carotenoids.

  本发明涉及将新的生物合成途径，特别是类胡萝卜素生物合成途径工程化到微生物中。新的和改进的代谢途径的催化功能是通过特定位点突变或基因重组等技术创造出来的，以提供高效的类胡萝卜素生物合成。通过应用所述的定向进化技术，几乎任何类胡萝卜素都可以在宿主细胞中由一组或几组基因产生。此外，所述技术还可用于创建基因或蛋白质文库，以获得新的和未定性的类胡萝卜素。
• DIRECTED EVOLUTION OF BIOSYNTHETIC AND BIODEGRATION PATHWAYS
  申请人：CALIFORNIA INSTITUTE OF TECHNOLOGY

  公开号：EP1238068A1

  公开（公告）日：2002-09-11
• [EN] DIRECTED EVOLUTION OF BIOSYNTHETIC AND BIODEGRATION PATHWAYS<br/>[FR] EVOLUTION DIRIGEE DE VOIES DE BIOSYNTHESE ET DE BIODEGRADATION
  申请人：CALIFORNIA INST OF TECHN

  公开号：WO2001042455A1

  公开（公告）日：2001-06-14

  The present invention relates to engineering new biosynthetic pathways into microorganisms, in particular biosynthetic carotenoid pathways. New and improved catalytic functions of metabolic pathways are created by, for example, site-specific mutation or gene shuffling techniques, to provide for efficient biosynthesis of carotenoids. By applying the described directed evolution techniques, almost any carotenoid could be produced, in a host cell, from one or a few sets of genes. In addition, the described techniques are useful for creating gene or protein libraries for new and uncharacterized carotenoids.