2-[2-(4-chlorophenyl)propyl]malononitrile | 1158080-76-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[2-(4-chlorophenyl)propyl]malononitrile
• 英文别名: [2-(4-chlorophenyl)propyl]propanedinitrile；2-[2-(4-Chlorophenyl)propyl]propanedinitrile
• CAS: 1158080-76-2
• 化学式: C₁₂H₁₁ClN₂
• 分子量: 218.686
• InChiKey: MGSNPIMTLYFLHT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  47.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-氯苯乙烯 、 一氧化碳 、 丙二腈 在 chloro(1,5-cyclooctadiene)rhodium(I) dimer 、 氢气 、 sodium 3-(diphenylphosphanyl)benzenesulfonate 作用下， 以 四氢呋喃 、 1,2-二氯乙烷 为溶剂， 80.0 ℃ 、4.14 MPa 条件下， 反应 14.0h， 以94%的产率得到2-[2-(4-chlorophenyl)propyl]malononitrile
  参考文献：
  名称：

  溶胶-凝胶包埋铑配合物、固定化碱和离子液体的一锅法选择性加氢甲酰化、缩合和加氢过程

  摘要：

  我们报告了一种一锅多步工艺，其中苯乙烯衍生物被选择性加氢甲酰化以产生支化醛，而支链醛又与反应性亚甲基化合物（丙二腈、氰基乙酸乙酯）缩合，然后氢化。该过程在 80 °C 和 20.7 bar H2 和 20.7 bar CO 下在 [Rh(cod)Cl]2 和 Na[Ph2P-3-(C6H4SO3)] 存在下进行，它们已被共包埋在离子液体中硅溶胶-凝胶与单独封装的底座一起。催化剂至少可以重复使用四次，但每次运行后必须更新碱。(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

  DOI：

  10.1002/ejoc.200801258

文献信息

• Rhodium-complexed hyperbranched poly(ethyleneimine) and polyamidoamine and their non-covalent immobilization on magnetic nanoparticles
  作者：Suheir Omar、Bishnu Dutta、Suzana Natour、Raed Abu-Reziq

  DOI：10.1016/j.jorganchem.2016.05.021

  日期：2016.9

  strategy for the synthesis and functionalization of hyperbranched poly(ethyleneimine) (H-PEI) and polyamidoamine (H-PAMAM) with phosphine ligands and their non-covalent immobilization on magnetic nanosupports. Treatment of these functionalized hyperbranched polymers with Rh(COD)2BF4 affords polymer-bound Rh(I) complexes that can be utilized in the hydroformylation of alkenes and in one pot hydroformyla

  我们描述了一种合成策略，用于合成和功能化具有膦配体的超支化聚（乙烯亚胺）（H-PEI）和聚酰胺基胺（H-PAMAM）以及它们在磁性纳米载体上的非共价固定化。用Rh（COD）2 BF 4处理这些官能化的超支化聚合物可得到与聚合物结合的Rh（I）配合物，可用于烯烃的加氢甲酰化反应和一锅加氢甲酰化-Knoevenagel加氢反应中。这些功能化的超支化聚合物与磁性纳米粒子相连，磁性纳米粒子通过由酸碱反应引起的离子相互作用，并有助于促进聚合催化剂的分离。这些磁性可回收的聚合物催化剂可以重复使用多达四个循环。
• EP1385377A1
  申请人：——

  公开号：EP1385377A1

  公开（公告）日：2004-02-04
• MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES
  申请人：SUMITOMO CHEMICAL COMPANY LIMITED

  公开号：EP1392647A1

  公开（公告）日：2004-03-03
• [EN] PESTICIDE COMPOSITION COMPRISING MALONONITRILE COMPOUNDS<br/>[FR] COMPOSITION PESTICIDE COMPRENANT DES COMPOSES DE MALONONITRILE
  申请人：SUMITOMO CHEMICAL CO

  公开号：WO2002089579A1

  公开（公告）日：2002-11-14

  The present invention relates to use of malononitrile compounds of formula (X): wherein R1 and R2 are the same or different and independently C1-C5 (halo)alkyl, C1-C5 (halo)alkyloxy, C2-C5 (halo)alkenyl, C2-C5 (halo)alkynyl, hydrogen, or cyano; R¿3? and R4 are the same or different and independently C?1-C10¿ alkyl, C2-C10 alkenyl, C2-C10 alkynyl, or hydrogen, or R¿3? and R4 are taken together to form C?2-C6¿ (halo)alkylene or C4-C6 (halo)alkenylene; R¿5? is halogen, cyano, nitro, C?1-C4¿ (halo)alkyl, or the like; n is an integer of 0 to 4; R¿6? is halogen, cyano, nitro, C?1-C4¿ (halo)alkyl, or the like; or R¿5? and R6 are taken together to form methylenedioxy; with the provisos that when R6 is hydrogen, then n is an integer of 1 to 4 and that when n is 2 or more, then R5's are different from each other; as pesticides, and to pesticide compositions containing these compounds as active ingredients. The present invention makes it possible to effectively control pests such as insect pests, acarine pests, and nematode pests.
• [EN] MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES<br/>[FR] COMPOSES DE MALONONITRILE ET LEUR UTILISATION EN TANT QUE PESTICIDES
  申请人：SUMITOMO CHEMICAL CO

  公开号：WO2002090321A1

  公开（公告）日：2002-11-14

  The present invention relates to malononitrile compounds of formula (Y):wherein R1 and R2 are the same or different and independently C1-C5 (halo)alkyl, C1-C5 (halo)alkyloxy, C2-C5 (halo)alkenyl, C2-C5 (halo)alkynyl, hydrogen, or cyano; R¿3? is C?3-C6¿ (halo)cycloalkyl; m is an integer of 1 to 3; R¿5? is halogen, cyano, nitro, C?1-C4¿ (halo)alkyl, or the like; n is an integer of 0 to 4, with the proviso that when n is 2 or more, then R¿5'?s are the same or different from each other; R6 is halogen, cyano, nitro, C?1-C4¿ (halo)alkyl, or the like; as well as pesticide compositions containing these compounds as active ingredients. The present invention makes it possible to effectively control pests such as insect pests, acarine pests, and nematode pests.