5,6-epoxycyclohexadecanone | 253309-55-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5,6-epoxycyclohexadecanone
• 英文别名: 17-Oxabicyclo[14.1.0]heptadecan-5-one
• CAS: 253309-55-6
• 化学式: C₁₆H₂₈O₂
• 分子量: 252.397
• InChiKey: ALXFTKOMFZPMIR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  29.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5,6-epoxycyclohexadecanone 在 sodium hydroxide 、 sodium hydridoborate 、 水 作用下， 以 甲醇 为溶剂， 反应 4.0h， 生成 17-Oxabicyclo[14.1.0]heptadecan-5-ol
  参考文献：
  名称：

  US2008/234174

  摘要：

  公开号：
• 作为产物：
  描述：

  cyclohexadec-5-en-1-one 在 过氧乙酸 、 sodium acetate 作用下， 以 二氯甲烷 为溶剂， 反应 6.0h， 生成 5,6-epoxycyclohexadecanone
  参考文献：
  名称：

  US2008/234174

  摘要：

  公开号：

文献信息

• A Practical Method for Alcohol Oxidation with Aqueous Hydrogen Peroxide under Organic Solvent- and Halide-Free Conditions
  作者：Kazuhiko Sato、Masao Aoki、Junko Takagi、Klaus Zimmermann、Ryoji Noyori

  DOI：10.1246/bcsj.72.2287

  日期：1999.10

  A catalytic system consisting of sodium tungstate and methyltrioctylammonium hydrogensulfate effects oxidation of simple secondary alcohols to ketones using 3—30% H2O2 without any organic solvents. The oxidation can be conducted under entirely halide-free, mildly acidic conditions. A combination of tungstic acid and an appropriate quaternary ammonium salt also effects the alcohol dehydrogenation. The

  由钨酸钠和甲基三辛基硫酸氢铵组成的催化体系使用 3-30% 的 H2O2 在没有任何有机溶剂的情况下将简单的仲醇氧化成酮。氧化可以在完全不含卤化物的弱酸性条件下进行。钨酸和合适的季铵盐的组合也影响醇脱氢。有机/水双相反应允许容易的产物/催化剂分离。转化数，定义为每摩尔催化剂的产物摩尔数，接近 77700（2-辛醇）或 179000（1-苯基乙醇），比之前报道的任何数量级高两个数量级。酯、烷基和叔丁基二甲基甲硅烷基醚、环氧基、羰基、N-烷基甲酰胺和腈基团在反应条件下是可以耐受的。仲醇优先于末端烯烃氧化。伯链烷醇以中等至高产率直接氧化为羧酸。苯甲醇被选择性氧化成...
• Macrocyclic musks
  申请人：Turin Luca

  公开号：US20070032401A1

  公开（公告）日：2007-02-08

  A compound comprising a macrocyclic ketone having at least one double bond and 15-20 carbon atoms, wherein at least one double bond has been converted to oxirane or thiirane or a macrocyclic lactone or dilactone having at least one double bond and 14-19 carbon atoms, wherein at least one double bond has been converted to oxirane or thiirane; or one of said oxiranes or thiiranes containing a methyl substituent on the ring and/or an ether oxygen or thioether sulfur substituting for a CH 2 somewhere in the ring and compositions, products, preparations or articles having improved aroma, fragrance, odor, flavor and/or taste characteristics containing as active ingredient a compound or mixture of the compounds.
• FURANOID AND PYRANOID C14-C18- OXABICYCLOALKANONES AS ODORIFEROUS AND/OR AROMA SUBSTANCES
  申请人：Hoelscher Bernd

  公开号：US20080234174A1

  公开（公告）日：2008-09-25

  The present invention relates to compounds of the formula (I) and the formula (Ia) wherein R 1 , R 2 and R 3 mutually independently mean hydrogen or methyl, odoriferous and/or aroma substance compositions comprising one or more compounds according to the invention of the formula (I) and/or formula (Ia), perfumed products and aromatized products in each case comprising one or more compounds according to the invention of the formula (I) and/or formula (Ia), and to uses of one or more compounds according to the invention of the formula (I) and/or formula (Ia) as odoriferous and/or aroma substances and methods of producing compounds according to the invention of the formula (I) and formula (Ia).
• US7615526B2
  申请人：——

  公开号：US7615526B2

  公开（公告）日：2009-11-10