octyl 4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranoside | 1240385-95-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: octyl 4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranoside
• CAS: 1240385-95-8
• 化学式: C₈₈H₉₈O₂₁
• 分子量: 1491.73
• InChiKey: MZKHVNDFEROBAH-YUTLEEIJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.1
• 重原子数：
  109.0
• 可旋转键数：
  34.0
• 环数：
  12.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  236.19
• 氢给体数：
  1.0
• 氢受体数：
  21.0

反应信息

• 作为反应物：
  描述：

  3-O-acetyl-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl trichloroacetimidate 、 octyl 4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranoside 在 TMSOTf 作用下， 以 二氯甲烷 为溶剂， 以92%的产率得到octyl 3-O-acetyl-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranoside
  参考文献：
  名称：

  Convenient synthesis of sulfated oligofucosides

  摘要：

  Two types of sulfated octyl tetra- to octaoligofucosides with different sulfation patterns were synthesized employing a combination of stepwise elongation and convergent strategies in which trichloroacetimidates and thioglycosides were selected as the glycosyl donors. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2010.04.006
• 作为产物：
  描述：

  octyl 3-O-acetyl-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranoside 在 甲醇 、 乙酰氯 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以86.8%的产率得到octyl 4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranosyl-(1->3)-4-O-benzoyl-2-O-benzyl-α-L-fucopyranoside
  参考文献：
  名称：

  Convenient synthesis of sulfated oligofucosides

  摘要：

  Two types of sulfated octyl tetra- to octaoligofucosides with different sulfation patterns were synthesized employing a combination of stepwise elongation and convergent strategies in which trichloroacetimidates and thioglycosides were selected as the glycosyl donors. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2010.04.006