(Z,Z)-2,2'-thiobis(3-(4-chlorophenyl)-1-p-tolylprop-2-en-1-one) | 754189-26-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: (Z,Z)-2,2'-thiobis(3-(4-chlorophenyl)-1-p-tolylprop-2-en-1-one)
• CAS: 754189-26-9
• 化学式: C₃₂H₂₄Cl₂O₂S
• 分子量: 543.513
• InChiKey: JFKSVRIULYOZAC-NAZWXXJZSA-N

反应信息

• 作为反应物：
  描述：

  硝基甲烷 、 (Z,Z)-2,2'-thiobis(3-(4-chlorophenyl)-1-p-tolylprop-2-en-1-one) 在 sodium ethanolate 作用下， 以 乙醇 为溶剂， 反应 0.13h， 以78%的产率得到3a,5e-di(p-chlorophenyl)-2a,6e-di(p-methylbenzoyl)-4e-nitrothiane
  参考文献：
  名称：

  Stereoselective Synthesis of Polyfunctionalized Nitrothianes: Enhancement of Stereoselectivity by Microwaves

  摘要：

  The Michael addition of nitromethane to (Z,Z)-2,2-thiobis(1,3-diarylprop-2-en-1-ones) in the presence of NaOEt in dimethylformamide (DMF)/alcohol under thermal conditions affords a diastereomeric mixture of 2a,6e-diaroyl-3a,5e-diaryl-4e-nitrothianes and 2e,6e-diaroyl-3e,5e-diaryl-4e-nitrothianes with a dr of approximate to 3:1/4:1 respectively. This reaction under microwave irradiation in DMF/alcohol afforded solely 2a,6e-diaroyl-3a,5e-diaryl-4e-nitrothianes, disclosing enhancement of stereoselectivity by microwaves. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) to view the free supplemental file.

  DOI：

  10.1080/00397911.2012.683970