[2-[2,6-Di(propan-2-yl)phenyl]-3,3-dimethyl-2-azaspiro[4.5]decan-1-ylidene]-(2,2,6,6-tetramethylpiperidin-1-yl)phosphane | 1239320-32-1

• 分子结构分类: 有机化合物 - 生物碱及其衍生物
• 英文名称: [2-[2,6-Di(propan-2-yl)phenyl]-3,3-dimethyl-2-azaspiro[4.5]decan-1-ylidene]-(2,2,6,6-tetramethylpiperidin-1-yl)phosphane
• CAS: 1239320-32-1
• 化学式: C₃₂H₅₃N₂P
• 分子量: 496.76
• InChiKey: MQQFNXAMPPFIAP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.5
• 重原子数：
  35
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  [2-[2,6-Di(propan-2-yl)phenyl]-3,3-dimethyl-2-azaspiro[4.5]decan-1-ylidene]-(2,2,6,6-tetramethylpiperidin-1-yl)phosphane 、 三苯碳四(五氟苯基)硼酸盐 以 苯 为溶剂， 反应 1.0h， 以38%的产率得到
  参考文献：
  名称：

  A Crystalline Phosphinyl Radical Cation

  摘要：

  One-electron oxidation of a readily available phosphaalkene derived from a cyclic (alkyl)(amino)carbene affords a phosphorus-centered radical cation that is indefinitely stable both in solution and in the solid state, allowing a single X-ray diffraction study to be performed. This species can be regarded as a phosphinyl radical bearing a cationic substituent or, alternatively, as a carbene-stabilized phospheniumyl radical (carbene-RP+center dot).

  DOI：

  10.1021/ja1046846
• 作为产物：
  描述：

  1-(chloro(2,2,6,6-tetramethylpiperidin-1-yl)phosphaneyl)-2-(2,6-diisopropylphenyl)-3,3-dimethyl-2-azaspiro[4.5]dec-1-en-2-ium chloride 在 magnesium 作用下， 以 四氢呋喃 为溶剂， 以81%的产率得到[2-[2,6-Di(propan-2-yl)phenyl]-3,3-dimethyl-2-azaspiro[4.5]decan-1-ylidene]-(2,2,6,6-tetramethylpiperidin-1-yl)phosphane
  参考文献：
  名称：

  A Crystalline Phosphinyl Radical Cation

  摘要：

  One-electron oxidation of a readily available phosphaalkene derived from a cyclic (alkyl)(amino)carbene affords a phosphorus-centered radical cation that is indefinitely stable both in solution and in the solid state, allowing a single X-ray diffraction study to be performed. This species can be regarded as a phosphinyl radical bearing a cationic substituent or, alternatively, as a carbene-stabilized phospheniumyl radical (carbene-RP+center dot).

  DOI：

  10.1021/ja1046846