6-(3-Methoxy-phenoxy)-3-methyl-pyridin | 93189-27-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-(3-Methoxy-phenoxy)-3-methyl-pyridin
• 英文别名: 6-<3-Methoxy-phenoxy>-3-methyl-pyridin；2-(3-methoxy-phenoxy)-5-methyl-pyridine；2-(3-Methoxyphenoxy)-5-methylpyridine
• CAS: 93189-27-6
• 化学式: C₁₃H₁₃NO₂
• 分子量: 215.252
• InChiKey: GQCQOVXJMJFVBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  31.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] MCL1 INHIBITORS AND USES THEREOF<br/>[FR] INHIBITEURS DE MCL1 ET LEURS UTILISATIONS
  申请人：CALIFORNIA INST OF TECHN

  公开号：WO2021067827A1

  公开（公告）日：2021-04-08

  The present disclosure provides compounds, such as compounds of Formula I, and compositions that are MCL1 inhibitors.

  本公开提供了化合物，例如式I的化合物，以及作为MCL1抑制剂的组合物。
• PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND
  申请人：Taisho Pharmaceutical Co., Ltd.

  公开号：EP2881384B1

  公开（公告）日：2018-05-30
• [EN] SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF<br/>[FR] N-(1H-INDOL-7-YL)BENZÈNESULFONAMIDES À SUBSTITUTION SULFONAMIDE ET LEURS UTILISATIONS
  申请人：[en]TRIANA BIOMEDICINES, INC.

  公开号：WO2022169755A1

  公开（公告）日：2022-08-11

  The present application discloses novel compounds of formula (I), pharmaceutical compositions containing these compounds and methods of inducing degradation of a protein, comprising contacting the protein with an effective amount of a compound of the disclosure. Methods of treating disease and disorders that results from abnormal activity of a target protein in a subject, are also disclosed.