| 502590-85-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• CAS: 502590-85-4
• 化学式: C₁₅H₁₀O₇*C₄₂H₇₀O₃₅
• 分子量: 1437.24
• InChiKey: UWGJKZVIVNIGNL-ZQOBQRRWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -13.24
• 重原子数：
  99.0
• 可旋转键数：
  8.0
• 环数：
  24.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  685.41
• 氢给体数：
  26.0
• 氢受体数：
  42.0

反应信息

• 作为产物：
  描述：

  桑色素 、 β-环糊精 以 水 为溶剂， 生成
  参考文献：
  名称：

  Complexation of morin with three kinds of cyclodextrin

  摘要：

  Properties of inclusion complexes between morin (M) and beta-cyclodextrin (beta CD), 2-hydroxypropyl-beta-cyclodextrin (HP beta CD) and Heptakis (2,6-O-di methyl) beta-cycloclextrin (DM beta CD) such as aqueous solubility and the association constants of this complex have been determined. The water solubility of morin was increased by inclusion with cyclodextrins. The phase-solubility diagrams drawn from UV spectral measurements are of the A(L)-type. Also ORAC(FL). studies were done. An increase in the antioxidant reactivity is observed when morin form inclusion complex with the three cyclodextrin studied. Finally, thermodynamics studies of cyclodextrin complexes indicated that for DM beta CD the inclusion is primarily enthalpy-driven process meanwhile beta CD and HP beta CD are entropy-driven processes. This is corroborated by the different inclusion geometries obtained by 2D-NMR. (C) 2007 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2007.12.020