4-methoxyphenyl (2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->3)-(β-D-galactopyranosyl)-(1->4)-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-(1->3)-(β-D-galactopyranosyl)-(1->4)-β-D-glucopyranoside | 1064679-28-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-methoxyphenyl (2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->3)-(β-D-galactopyranosyl)-(1->4)-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-(1->3)-(β-D-galactopyranosyl)-(1->4)-β-D-glucopyranoside
• CAS: 1064679-28-2
• 化学式: C₄₁H₆₄N₂O₂₇
• 分子量: 1016.96
• InChiKey: XYCHMNQJXXLDSW-MKDRGJLSSA-N

反应信息

• 作为产物：
  描述：

  [(2R,3S,4S,5R,6S)-3-acetyloxy-6-[(2R,3S,4R,5R,6S)-6-[(2S,3R,4S,5S,6R)-5-acetyloxy-2-[(2R,3R,4S,5R,6S)-6-(4-methoxyphenoxy)-4,5-bis(phenylmethoxy)-2-(phenylmethoxymethyl)oxan-3-yl]oxy-3-phenylmethoxy-6-(phenylmethoxymethyl)oxan-4-yl]oxy-5-(1,3-dioxoisoindol-2-yl)-4-hydroxy-2-(phenylmethoxymethyl)oxan-3-yl]oxy-5-benzoyloxy-4-[(2S,3R,4R,5R,6R)-4,5-diacetyloxy-6-(acetyloxymethyl)-3-(1,3-dioxoisoindol-2-yl)oxan-2-yl]oxyoxan-2-yl]methyl benzoate 以70%的产率得到4-methoxyphenyl (2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->3)-(β-D-galactopyranosyl)-(1->4)-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-(1->3)-(β-D-galactopyranosyl)-(1->4)-β-D-glucopyranoside
  参考文献：
  名称：

  Concise synthesis of two pentasaccharides corresponding to the α-chain oligosaccharides of Neisseria gonorrhoeae and Neisseria meningitidis

  摘要：

  Two pentasaccharides containing a common tetrasaccharide (lacto-N-neotetraose) core, and D-galactosamine and N-acetyl neuraminic acid in the non-reducing ends, respectively, corresponding to the lipooligosaccharides of Neisseria gonorrhoeae and Neisseria meningitidis were synthesized in a very concise manner from a common trisaccharide derivative using minimum number of steps. Thioglycosides and glycosyl trichloroacetimidate have been used as glycosyl donors for glycosylations and yields were excellent in every step. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.07.004