1-methyl-3-acetylpyridinium chloride | 7629-96-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-methyl-3-acetylpyridinium chloride
• 英文别名: 1-(1-Methylpyridin-1-ium-3-yl)ethanone;chloride
• CAS: 7629-96-1
• 化学式: C₈H₁₀NO*Cl
• 分子量: 171.626
• InChiKey: NPAQVGZWNPJMOL-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -2.28
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  21
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-甲基吲哚 、 1-methyl-3-acetylpyridinium chloride 以95%的产率得到
  参考文献：
  名称：

  ALVAREZ, MERCEDES;LAVILLA, RODOLFO;BOSCH, JOAN, HETEROCYCLES, 29,(1989) N, C. 237-242

  摘要：

  DOI：

文献信息

• USE OF QUATERNARY PYRIDINIUM SALTS FOR RADIOPROTECTION
  申请人：Politechnika Lodzka

  公开号：EP2211857A1

  公开（公告）日：2010-08-04
• USE OF QUATERNARY PYRIDINIUM SALTS FOR INHIBITING CANCER METASTASES
  申请人：Politechnika Lodzka

  公开号：EP2211858B1

  公开（公告）日：2015-03-25
• Method for inhibiting and/or preventing formation of cancer metastases and seconddary malignant cancers
  申请人：Gebicki Jerzy

  公开号：US20090118340A1

  公开（公告）日：2009-05-07

  The invention relates to a method for inhibiting and/or preventing formation of cancer metastases and secondary malignant cancers by administration to a subject of an effective amount of a quaternary pyridinium salt of formula I wherein R′ is selected from the group consisting of H, OH, CONH 2 , COCH 3 , R″ is selected from the group consisting of H, CH 3 , R′″ represents H or CH 3 , and X − is a pharmaceutically acceptable counterion.
• METHOD FOR INHIBITING AND/OR PREVENTING FORMATION OF CANCER METASTASES AND SECONDARY MALIGNANT CANCER
  申请人：Gebicki Jerzy

  公开号：US20110201653A1

  公开（公告）日：2011-08-18

  The invention relates to a method for inhibiting and/or preventing formation of cancer metastases and secondary malignant cancers by administration to a subject of an effective amount of a quaternary pyridinium salt of formula I wherein R′ is selected from the group consisting of H, OH, CONH 2 , COCH 3 , R″ is selected from the group consisting of H, CH 3 , R′″ represents H or CH 3 , and X − is a pharmaceutically acceptable counterion.
• US8304439B1
  申请人：——

  公开号：US8304439B1

  公开（公告）日：2012-11-06