(E)-2-[2-((S)-2-{(S)-2-[2-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-acetylamino]-4-methyl-pentanoylamino}-3-phenyl-propionylamino)-acetylamino]-3-(toluene-4-sulfonyloxy)-acrylic acid methyl ester | 855739-07-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (E)-2-[2-((S)-2-{(S)-2-[2-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-acetylamino]-4-methyl-pentanoylamino}-3-phenyl-propionylamino)-acetylamino]-3-(toluene-4-sulfonyloxy)-acrylic acid methyl ester
• CAS: 855739-07-0
• 化学式: C₄₀H₅₆N₆O₁₂S
• 分子量: 844.984
• InChiKey: SZXWINQJHUSXKR-RRURFNPQSA-N

反应信息

• 作为反应物：
  描述：

  (E)-2-[2-((S)-2-{(S)-2-[2-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-acetylamino]-4-methyl-pentanoylamino}-3-phenyl-propionylamino)-acetylamino]-3-(toluene-4-sulfonyloxy)-acrylic acid methyl ester 在 三乙胺 、 三氟乙酸 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 21.0h， 生成 (Z)-(5S,11S,14S)-14-Benzyl-11-isobutyl-5-isopropyl-6,9,12,15,18-pentaoxo-1,4,7,10,13,16-hexaaza-cyclooctadec-2-ene-2-carboxylic acid methyl ester
  参考文献：
  名称：

  Synthesis of Cyclic Endiamino Peptides

  摘要：

  Several building blocks for endiamino peptides, as well as several cyclic endiamino peptides themselves, and pyrazin-6-one, which embodies the endiamino group, were prepared. The variety of synthesized compounds shows the potential of this synthesis in the preparation of many different groups of compounds.

  DOI：

  10.1021/ja050299r
• 作为产物：
  描述：

  Boc-L-Val-Gly-L-Leu-L-Phe-Gly-L-Ser-OMe 、 对甲苯磺酰氯 在 二甲基亚砜 、 三乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以70%的产率得到(E)-2-[2-((S)-2-{(S)-2-[2-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-acetylamino]-4-methyl-pentanoylamino}-3-phenyl-propionylamino)-acetylamino]-3-(toluene-4-sulfonyloxy)-acrylic acid methyl ester
  参考文献：
  名称：

  Synthesis of Cyclic Endiamino Peptides

  摘要：

  Several building blocks for endiamino peptides, as well as several cyclic endiamino peptides themselves, and pyrazin-6-one, which embodies the endiamino group, were prepared. The variety of synthesized compounds shows the potential of this synthesis in the preparation of many different groups of compounds.

  DOI：

  10.1021/ja050299r