1-(2-chloro-5-thiazolylmethyl)-1-methoxycarbonyl-3-methyl-2-nitroguanidine | 141205-50-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-(2-chloro-5-thiazolylmethyl)-1-methoxycarbonyl-3-methyl-2-nitroguanidine
• 英文别名: methyl N-[(2-chloro-1,3-thiazol-5-yl)methyl]-N-[(Z)-N-methyl-N'-nitrocarbamimidoyl]carbamate
• CAS: 141205-50-7
• 化学式: C₈H₁₀ClN₅O₄S
• 分子量: 307.717
• InChiKey: AVVWWPJQLHPPOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  141
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  N-(2-chloro-5-thiazolylmethyl)-N-methoxycarbonyl-S-methyl-N'-nitroisothiourea 、 methylaminomethanol 以 甲醇 为溶剂， 生成 1-(2-chloro-5-thiazolylmethyl)-1-methoxycarbonyl-3-methyl-2-nitroguanidine
  参考文献：
  名称：

  Substituted guanidine derivatives, their preparation and use

  摘要：

  新型替代硝基胍衍生物及其盐具有以下结构式：##STR1## 其中R.sup.1是取代或未取代的杂环基团；R.sup.2是通过硫原子连接的基团，通过磷原子连接的基团，氰基，--CO--OR.sup.6，其中R.sup.6是取代或未取代的碳氢基团或取代或未取代的杂环基团，或--CO--NR.sup.7 R.sup.8，其中R.sup.7和R.sup.8，相同或不同，各自独立地是氢、取代或未取代的碳氢基团或取代或未取代的杂环基团，或R.sup.7和R.sup.8，与它们连接的氮原子一起构成一个环状氨基团；R.sup.3是氢、取代或未取代的碳氢基团（除了一个在结合位点上取代了氧代基的基团）、通过硫原子连接的基团，通过磷原子连接的基团，氰基，--CO--R.sup.9，其中R.sup.9是氢、取代或未取代的碳氢基团或取代或未取代的杂环基团，--CO--OR.sup.10，其中R.sup.10是取代或未取代的碳氢基团或取代或未取代的杂环基团，或--CO--NR.sup.11 R.sup.12，其中R.sup.11和R.sup.12，相同或不同，各自独立地是氢、取代或未取代的碳氢基团或取代或未取代的杂环基团，或R.sup.11和R.sup.12，与它们连接的氮原子一起构成一个环状氨基团；和R.sup.4是氢或低碳基团；这些化合物具有意外强大的杀虫活性和极低的毒性。

  公开号：

  US05256679A1

文献信息

• Novel substituted guanidine derivatives, their preparation and use
  申请人：Takeda Chemical Industries, Ltd.

  公开号：EP0471372A1

  公开（公告）日：1992-02-19

  Novel substituted nitroguanidine derivatives and salts thereof having the following formula: wherein R¹ is a substituted or unsubstituted heterocyclic group; R² is a group attached through a sulfur atom, a group attached through a phosphorus atom, cyano, -CO-OR⁶ wherein R⁶ is a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or -CO-NR⁷R⁸ wherein R⁷ and R⁸, which are the same or different, are each independently hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or R⁷ and R⁸, taken together with the nitrogen atom to which they are attached are a cyclic amino group; R³ is hydrogen, a substituted or unsubstituted hydrocarbon group (except for one substituted with an oxo group at the binding site), a group attached through a sulfur atom, a group attached through a phosphorus atom, cyano, -CO-R⁹ wherein R⁹ is hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, -CO-OR¹⁰ wherein R¹⁰ is a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or -CO-NR¹¹R¹² wherein R¹¹ and R¹², which are the same or different, are each independently hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or R¹¹ and R¹², taken together with the nitrogen atom to which they are attached are a cyclic amino group; and R⁴ is hydrogen or a lower alkyl group; which have unexpectedly potent pesticidal activity and very low toxicity.

  具有下式的新型取代硝基胍衍生物及其盐类： 其中 R¹ 是取代或未取代的杂环基团；R² 是通过硫原子连接的基团、通过磷原子连接的基团、氰基、-CO-OR⁶ 其中 R⁶ 是取代或未取代的烃基或取代或未取代的杂环基，或 -CO-NR⁷R⁸ 其中 R⁷ 和 R⁸、相同或不同，各自独立地为氢、取代或未取代的烃基或取代或未取代的杂环基，或 R⁷ 和 R⁸ 与它们所连接的氮原子一起为环状氨基；R³ 是氢、取代或未取代的烃基（在结合位点被氧代基团取代的除外）、通过硫原子连接的基团、通过磷原子连接的基团、氰基、-CO-R⁹，其中 R𠞙 是氢、取代或未取代的烃基或取代或未取代的杂环基团、-CO-OR¹⁰，其中 R¹⁰ 是取代或未取代的烃基或取代或未取代的杂环基，或-CO-NR¹R¹²，其中 R¹¹ 和 R¹² (相同或不同)各自独立地是氢、取代或未取代的烃基或取代或未取代的杂环基，或 R¹¹ 和 R¹² 与它们所连接的氮原子一起是环状氨基；和 R⁴ 是氢或低级烷基；它们具有意想不到的强杀虫活性和极低的毒性。
• GYPSUM BOARD AND PROCESS FOR PRODUCING GYPSUM BOARD
  申请人：Yoshino Gypsum Co., Ltd.

  公开号：EP3392223A1

  公开（公告）日：2018-10-24

  A gypsum panel includes a gypsum core containing a termite repellent with poor water solubility, wherein the gypsum core has a first end region, a center region, and a second end region having an equal thickness and extending along a thickness direction from one surface side to another surface side, the termite repellent is contained in each of the first end region, the center region, and the second end region, and a content of the termite repellent in the center region is lower than a content of the termite repellent in the first end region and in the second end region.

  一种石膏板包括含有水溶性差的白蚁驱避剂的石膏芯材，其中石膏芯材具有第一端区域、中心区域和第二端区域，这些区域的厚度相等，并沿厚度方向从一个表面侧延伸到另一个表面侧，白蚁驱避剂分别包含在第一端区域、中心区域和第二端区域中，且中心区域中白蚁驱避剂的含量低于第一端区域和第二端区域中白蚁驱避剂的含量。
• Gypsum panel and method for producing gypsum panel
  申请人：YOSHINO GYPSUM CO., LTD.

  公开号：US10968624B2

  公开（公告）日：2021-04-06

  A gypsum panel includes a gypsum core containing a termiticide with poor water solubility, wherein the gypsum core has a first end region, a center region, and a second end region having an equal thickness and extending along a thickness direction from one surface side to another surface side, the termiticide is contained in each of the first end region, the center region, and the second end region, and a content of the termiticide in the center region is lower than a content of the termiticide in the first end region and in the second end region.

  一种石膏板包括含有水溶性较差的杀白蚁剂的石膏芯材，其中石膏芯材具有第一端区域、中心区域和第二端区域，这些区域的厚度相等，并沿厚度方向从一个表面侧延伸到另一个表面侧，第一端区域、中心区域和第二端区域中均含有杀白蚁剂，且中心区域中的杀白蚁剂含量低于第一端区域和第二端区域中的杀白蚁剂含量。
• GYPSUM BOARD
  申请人：Yoshino Gypsum Co., Ltd.

  公开号：EP3392223B1

  公开（公告）日：2021-09-08
• Hardenable termite-controlling composition
  申请人：Yoshida Shinji

  公开号：US20070039235A1

  公开（公告）日：2007-02-22

  A termite-controlling layer is formed with a particulate hardenable termite-controlling composition which comprises a hydraulic material, a soil and/or a termiticide, on an area to be treated. The soil may comprise a gravel component and a fine grain component, and the weight ratio of the gravel component relative to the fine grain component may be about 99.9/0.1 to 5/95. The fine grain component may comprise a sand component and a dirt component, and the weight ratio of the sand component relative to the dirt component may be about 99/1 to 10/90. The hardenable termite-controlling composition may further comprise a biocidal component, a deodorant component, or a humidity-conditioning component. In a termite-controlling process, the termite-controlling layer may be formed by laying the hardenable termite-controlling composition on the area to be treated, and applying at least a water to the laid hardenable termite-controlling composition. The use of the composition can effectively control termites in an underfloor area of a wooden building or a park.