1-[(2-ethylamino-ethylimino)-methyl]-naphthalen-2-ol | 952481-58-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-[(2-ethylamino-ethylimino)-methyl]-naphthalen-2-ol
• 英文别名: 1-[2-(Ethylamino)ethyliminomethyl]naphthalen-2-ol
• CAS: 952481-58-2
• 化学式: C₁₅H₁₈N₂O
• 分子量: 242.321
• InChiKey: YPFRAKWSCWROMW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  44.6
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  copper chloride dihydrate 、 1-[(2-ethylamino-ethylimino)-methyl]-naphthalen-2-ol 以 甲醇 为溶剂， 反应 2.0h， 以68%的产率得到
  参考文献：
  名称：

  Copper(II) complexes with tridentate N2O donor Schiff base isomers: Modulation of molecular and crystalline architectures through supramolecular interactions

  摘要：

  Four copper(II) complexes, [Cu(L-1)(mu-Cl)](n) (1), [Cu-2(L-2)(2)(mu-Cl)(2)] (2), [Cu(L-1)(mu(1,5)-NCNCN)](n) (3) and [Cu(L-2)(mu(1,5)-NCNCN)](n), (4), where HL1 = 1-[(2-dimethylamino-ethylimino)-methyl]-naphthalen-2-ol and HL2 = 1-[(2-ethylamino-ethylimino)-methyl]-naphthalen-2-ol, acting as tridentate N2O donor ligands, have been prepared and characterized by elemental analysis, IR and UV-Vis spectroscopy and single crystal X-ray diffraction studies. Complexes 1, 3 and 4 show polymeric chain structures, whereas 2 has a double chloride bridged dimeric structure. The existence of C-H center dot center dot center dot pi it interactions between the dimeric units of 2 gives rise to a 2D supramolecular network. Complex 3 shows a zipper structure through pi center dot center dot center dot pi interactions between two polymeric chains. Complex 4 shows hydrogen bonding interactions which produces a 2D hydrogen bonded structure and these 2D layers then show interlayer pi center dot center dot center dot pi interactions. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2013.04.045
• 作为产物：
  描述：

  N-乙基乙二胺 、 2-羟基-1-萘甲醛 以 甲醇 为溶剂， 反应 0.5h， 生成 1-[(2-ethylamino-ethylimino)-methyl]-naphthalen-2-ol
  参考文献：
  名称：

  Control of molecular architecture by hydrogen bonding: mononuclear versus dinuclear copper(II) complexes with tridentate N2O donor Schiff base isomers

  摘要：

  HL 1  = 1-[(2-二甲基氨基-乙基亚氨基)-甲基]-萘-2-醇和 HL 2  = 1-[(2-乙基氨基-乙基亚氨基)-甲基]-萘-2-醇这两种异构席夫碱被用来在硫氰酸盐存在下制备铜（II）络合物。HL 1 与末端的硫氰酸盐形成单核络合物 [Cu(L1)NCS]，而异构席夫碱 HL 2 则能形成氢键，产生具有双 μ-1,1-NCS 桥的二聚络合物 [Cu2 (L 2 ) 2(NCS)2]。这两种配合物都通过物理化学和光谱方法以及单晶 X 射线衍射研究进行了表征。

  DOI：

  10.1007/s11243-012-9677-1

文献信息

• Two mononuclear nickel(II) complexes with Schiff base ligands: Synthesis, crystal structures, and antibacterial activities
  作者：Wei-Hang Sun、Lu-Lu Wu、Lei Ye、Yu Xin、Yan Zhang、Hui Liu、Kai-Wen Lv、Chao-Nan Shang、Zhonglu You、Wei Li

  DOI：10.1080/24701556.2017.1284126

  日期：2017.10.3

  Two new mononuclear nickel(II) complexes, [NiL1(NCS)] (1) and [Ni(L2)2]·2NO3 (2), where L1 is the deprotonated form of 1-[(2-ethylaminoethylimino)methyl]-naphthalen-2-ol, and L2 is the zwitterionic form of 2,4-dibromo-6-[(2-ethylaminoethylimino)methyl]phenol, have been prepared and characterized by physico-chemical methods and single-crystal X-ray diffraction. The Ni atoms in both complexes are in square

  两个新的单核镍（II）配合物[NiL 1（NCS）]（1）和[Ni（L 2）2 ]·2NO 3（2），其中L 1是1-[（2-乙基氨基乙基亚氨基）的去质子化形式）甲基]-萘-2-醇，L 2是2,4-二溴-6-[（（2-乙基氨基乙基亚氨基）甲基]酚的两性离子形式，已通过物理化学方法和单晶表征X射线衍射。两个络合物中的Ni原子呈正方形平面配位。在镍原子1被一个酚O，一个亚胺N，和L中的一个胺N-原子配位1配体和一种硫氰酸盐N原子。2中的Ni原子由两个L 2配体的两个酚盐O和两个亚胺N原子配位。配合物的晶体通过氢键稳定。已经研究了配合物的热稳定性。Schiff碱和复合物显示出有效的抗菌活性。
• Synthesis, Crystal Structures and Antibacterial Activities of Two Schiff Base Zinc(II) Complexes
  作者：Zhong‐Lu You、Qing‐Zhu Jiao

  DOI：10.1080/15533170601028165

  日期：2006.12.1

  Two new mononuclear Schiff base zinc(II) complexes, [ZnBr(2)L1] center dot CH3OH (1) and [ZnBr(2)L2] center dot H2O (2) (L1 = 1-[(2-ethylaminoethylimino) methyl] naphthalen-2-olate, L2 = 4 bromo-2-[(2=methylaminoethylimino)methyl] phenolate), have been obtained from a similar synthetic procedure. The complexes have been characterized by elemental analyses and single crystal X-ray determinations. In each of the complexes, the zinc(II) atom is four-coordinated by one imine N and one phenolate O atoms from a Schiff base ligand, and by two terminal Br atoms, forming a tetrahedral coordination. Except for the mononuclear zinc(II) complex moiety, complex 1 consists of a lattice MeOH molecule, while complex 2 consists of a lattice water molecule. Both of the lattice components in the complexes participate in the formation of hydrogen bonds. The Schiff base ligands and the two zinc(II) complexes showed potent antibacterial activities.
• Hui, Rui-Hua; Zhou, Peng; You, Zhong-Lu, Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 2009, vol. 48, # 8, p. 1102 - 1106
  作者：Hui, Rui-Hua、Zhou, Peng、You, Zhong-Lu

  DOI：——

  日期：——