| 1356855-04-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• CAS: 1356855-04-3
• 化学式: C₁₆H₁₂O₅*C₄₂H₇₀O₃₅
• 分子量: 1419.27
• InChiKey: BOMBMKNULZPPLK-ZQOBQRRWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -12.35
• 重原子数：
  98.0
• 可旋转键数：
  9.0
• 环数：
  24.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  633.95
• 氢给体数：
  23.0
• 氢受体数：
  40.0

反应信息

• 作为产物：
  描述：

  汉黄芩素 、 β-环糊精 反应 1.0h， 生成
  参考文献：
  名称：

  Studying on inclusion complexes of Wogonin with β-cyclodextrin and hydroxypropyl-cyclodextrin

  摘要：

  The formation of the complexes of Wogonin with beta-cyclodextrin (beta-CD) and hydroxypropyl-cyclodextrin (HP-beta-CD) was studied by fluorescence spectra and nuclear magnetic resonance spectroscopy (NMR). The formation constants (Ks) of complexes were determined by fluorescence method. The results suggested that HP-beta-CD was easier to form inclusion with Wogonin than beta-CD in solution. In different pH solutions, CDs have different inclusive capacity to Wo, beta-CD was most suitable for inclusion of neutral form and HP-beta-CD was suitable for acidic form. In addition, the experimental resulted confirmed the existence of 1:1 inclusion complex of Wogonin with CDs.Besides, kinetic studies of DPPH* with Wogonin and CDs complexes were done. The results obtained indicated that the complex was the most reactive form. Special configuration of complex has been proposed on NMR technique. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2011.10.057