formaldehyde dinonylacetal | 5137-14-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: formaldehyde dinonylacetal
• 英文别名: Bis-nonyloxy-methan；Dinonylformal；1-(Nonoxymethoxy)nonane
• CAS: 5137-14-4
• 化学式: C₁₉H₄₀O₂
• 分子量: 300.525
• InChiKey: DPPRULUPFLKJAR-UHFFFAOYSA-N

物化性质

• 沸点：
  360.8±15.0 °C(Predicted)
• 密度：
  0.846±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  21
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1-壬醇 、 alkaline earth salt of/the/ methylsulfuric acid 生成 formaldehyde dinonylacetal
  参考文献：
  名称：

  Causes of employee theft and strategies that HR managers can use for prevention

  摘要：

  DOI：

  10.1002/(sici)1099-050x(200021)39:1<51::aid-hrm5>3.0.co;2-5

文献信息

• Ruthenium-Catalyzed Synthesis of Dialkoxymethane Ethers Utilizing Carbon Dioxide and Molecular Hydrogen
  作者：Katharina Thenert、Kassem Beydoun、Jan Wiesenthal、Walter Leitner、Jürgen Klankermayer

  DOI：10.1002/anie.201606427

  日期：2016.9.26

  The synthesis of dimethoxymethane (DMM) by a multistep reaction of methanol with carbon dioxide and molecular hydrogen is reported. Using the molecular catalyst [Ru(triphos)(tmm)] in combination with the Lewis acid Al(OTf)3 resulted in a versatile catalytic system for the synthesis of various dialkoxymethane ethers. This new catalytic reaction provides the first synthetic example for the selective

  据报道，通过甲醇与二氧化碳和分子氢的多步反应合成二甲氧基甲烷（DMM）。将分子催化剂[Ru（triphos）（tmm）]与路易斯酸Al（OTf）3结合使用可形成用于合成各种二烷氧基甲烷醚的通用催化体系。这种新的催化反应为将二氧化碳和氢气选择性转化为甲醛氧化水平提供了第一个合成实例，从而使用这种重要的C 1来源打开了进入新分子结构的途径。
• PROCESS FOR PREPARING AN ALKOXYMETHYL ALKYNYL ETHER COMPOUND HAVING A TERMINAL TRIPLE BOND
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：US20210198172A1

  公开（公告）日：2021-07-01

  The present invention provides a process for preparing an alkoxymethyl alkynyl ether compound having a terminal triple bond of the following formula (4): H—C≡C(CH 2 ) a OCH 2 OCH 2 R (4), wherein R represents a hydrogen atom, an n-alkyl group having 1 to 9 carbon atoms, or a phenyl group, and “a” represents an integer of 1 to 10, the method comprising subjecting an alkynol compound having a terminal triple bond of the following formula (1): H—C≡C(CH 2 ) a OH (1), wherein “a” is as defined above, to an alkoxymethylation with a halomethyl alkyl ether compound of the following formula (3): RCH 2 OCH 2 X (3), wherein X represents a halogen atom, and R is as defined above, in the presence of a dialkylaniline compound of the following formula (2): [CH 3 (CH 2 ) b ][CH 3 (CH 2 ) c ]NC 6 H 5 (2), wherein b and c represent, independently of each other, an integer of 0 to 9, to form the alkoxymethyl alkynyl ether compound (4) having a terminal triple bond.

  本发明提供了一种制备具有以下式(4)的末端三键的烷氧甲基炔基醚化合物的方法：H—C≡C(CH2)aO O R (4)，其中R代表氢原子、具有1至9个碳原子的n-烷基基团或苯基，而“a”代表1至10的整数，所述方法包括将具有以下式(1)末端三键的炔醇化合物进行烷氧甲基化，其中H—C≡C( )aOH (1)，其中“a”如上所定义，与具有以下式(3)的卤甲基烷醚化合物进行反应：R O X (3)，其中X代表卤素原子，R如上所定义，在存在以下式(2)的二烷基苯胺化合物的情况下进行，[CH3( )b][CH3( )c]NC6H5(2)，其中b和c独立地代表0至9的整数，以形成具有末端三键的烷氧甲基炔基醚化合物(4)。
• Process for preparing an alkoxymethyl alkynyl ether compound having a terminal triple bond
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：US11384041B2

  公开（公告）日：2022-07-12

  The present invention provides a process for preparing an alkoxymethyl alkynyl ether compound having a terminal triple bond of the following formula (4): H—C≡C(CH2)aOCH2OCH2R (4), wherein R represents a hydrogen atom, an n-alkyl group having 1 to 9 carbon atoms, or a phenyl group, and “a” represents an integer of 1 to 10, the method comprising subjecting an alkynol compound having a terminal triple bond of the following formula (1): H—C≡C(CH2)aOH (1), wherein “a” is as defined above, to an alkoxymethylation with a halomethyl alkyl ether compound of the following formula (3): RCH2OCH2X (3), wherein X represents a halogen atom, and R is as defined above, in the presence of a dialkylaniline compound of the following formula (2): [CH3(CH2)b][CH3(CH2)c]NC6H5 (2), wherein b and c represent, independently of each other, an integer of 0 to 9, to form the alkoxymethyl alkynyl ether compound (4) having a terminal triple bond.

  本发明提供了一种制备具有下式(4)末端三键的烷氧基甲基炔基醚化合物的工艺：H-C≡C(CH2)aO O R(4)，其中 R 代表氢原子、具有 1 至 9 个碳原子的正烷基或苯基，且 "a "代表 1 至 10 的整数，该方法包括使具有下式(1)的末端三键的炔醇化合物：H-C≡C( )aOH(1)，其中 "a "如上定义，用下式(3)的卤代甲基烷基醚化合物进行烷氧基甲基化：R O X(3)，其中 X 代表卤素原子，R 如上定义，在下式(2)的二烷基苯胺化合物存在下进行烷氧基甲基化：[CH3( )b][CH3( )c]NC6H5(2)，其中 b 和 c 各自代表 0 至 9 的整数，形成具有末端三键的烷氧基甲基炔基醚化合物 (4)。
• FeCl₃-Catalyzed Self-Cleaving Deprotection of Methoxyphenylmethyl-Protected Alcohols
  作者：Yoshinari Sawama、Masahiro Masuda、Shota Asai、Ryota Goto、Saori Nagata、Shumma Nishimura、Yasunari Monguchi、Hironao Sajiki

  DOI：10.1021/acs.orglett.5b00106

  日期：2015.2.6

  4-Methoxyphenylmethyl ethers are widely utilized as alcohol protecting groups. FeCl3 effectively catalyzes the deprotection of methoxyphenylmethyl-type ethers in a self-cleaving manner to produce oligomeric derivatives and alcohols. Remarkably, the highly pure mother alcohols can be obtained without silica gel column chromatography by using the 2,4-dimethoxyphenylmethyl group as a protective group.
• Pernak; Skrzypczak; Michalak, Pharmazie, 1988, vol. 43, # 9, p. 654 - 655
  作者：Pernak、Skrzypczak、Michalak、Krysinski

  DOI：——

  日期：——