2,3-O-isopropylidene-D-tartaric acid methyl ester amide | 342896-26-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3-O-isopropylidene-D-tartaric acid methyl ester amide
• 英文别名: methyl (4S,5S)-5-carbamoyl-2,2-dimethyl-1,3-dioxolane-4-carboxylate
• CAS: 342896-26-8
• 化学式: C₈H₁₃NO₅
• 分子量: 203.195
• InChiKey: OGYSIFXGUPXXQV-WHFBIAKZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  87.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2,3-O-isopropylidene-D-tartaric acid methyl ester amide 在 二异丁基氢化铝 作用下， 以 二氯甲烷 为溶剂， 反应 9.0h， 以94%的产率得到(4S,5S)-5-formyl-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid amide
  参考文献：
  名称：

  Synthesis of a building block for phosphonate analogues of moenomycin A12 from d-tartaric acid

  摘要：

  An approach for the synthesis of moenomycin A(12) C-glycoside partial structures is reported based on allyltin chemistry. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(01)00951-6
• 作为产物：
  描述：

  methyl (4S,5S)-2,2-dimethyl-1,3-dioxolane-4-carboxylic acid-5-carboxylate 以91%的产率得到2,3-O-isopropylidene-D-tartaric acid methyl ester amide
  参考文献：
  名称：

  Synthesis of a building block for phosphonate analogues of moenomycin A 12 from d -tartaric acid

  摘要：

  An approach for the synthesis of moenomycin A(12) C-glycoside partial structures is reported based on allyltin chemistry. (C) 2001 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(01)00350-1

文献信息

• Synthesis of a building block for phosphonate analogues of moenomycin A12 from d-tartaric acid
  作者：Jalal Zahra、Lothar Hennig、Matthias Findeisen、Sabine Giesa、Peter Welzel、Dietrich Müller、William S Sheldrick

  DOI：10.1016/s0040-4020(01)00951-6

  日期：2001.11

  An approach for the synthesis of moenomycin A(12) C-glycoside partial structures is reported based on allyltin chemistry. (C) 2001 Elsevier Science Ltd. All rights reserved.
• Synthesis of a building block for phosphonate analogues of moenomycin A 12 from d -tartaric acid
  作者：Jalal Zahra、Lothar Hennig、Matthias Findeisen、Peter Welzel、Dietrich Müller、William S Sheldrick

  DOI：10.1016/s0040-4039(01)00350-1

  日期：2001.4

  An approach for the synthesis of moenomycin A(12) C-glycoside partial structures is reported based on allyltin chemistry. (C) 2001 Published by Elsevier Science Ltd.