N-(5'-Phosphoribosyl)anthranilate | 4220-99-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-(5'-Phosphoribosyl)anthranilate
• 英文别名: 2-[[(3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]amino]benzoic acid
• CAS: 4220-99-9
• 化学式: C₁₂H₁₆NO₉P
• 分子量: 349.23
• InChiKey: PMFMJXPRNJUYMB-QHPFDFDXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  166
• 氢给体数：
  6
• 氢受体数：
  10

文献信息

• METHOD FOR PRODUCING ANILINE OR AN ANILINE CONVERSION PRODUCT
  申请人：Covestro Deutschland AG

  公开号：US20190233365A1

  公开（公告）日：2019-08-01

  The invention relates to a method for producing aniline or products that are obtained by further chemical reaction of aniline (aniline derivatives), involving decarboxylation of aminobenzoic acid, particularly ortho-aminobenzoic acid, in which one portion of the previously formed crude aniline is recirculated in the decarboxylation step. The aminobenzoic acid is obtained enzymatically or chemically, preferably enzymatically.

  该发明涉及一种生产苯胺或由苯胺（苯胺衍生物）进一步化学反应得到的产品的方法，包括氨基苯甲酸（特别是邻氨基苯甲酸）的脱羧反应，其中先前形成的粗苯胺的一部分在脱羧步骤中被再循环利用。氨基苯甲酸通过酶法或化学法获得，优选酶法。
• Biological screens for detection of herbicides
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0608722A1

  公开（公告）日：1994-08-03

  This invention pertains to novel protocols for the screening and rapid identification of compounds that specifically inhibit a predetermined enzyme or metabolic target site or pathway that is specific to plants. Enzymes which are specifically or indirected affected by the novel screens include glutamine synthetase (GS), 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAHP), dihydrodipicolinate synthase (DHPS), acetohydroxyacid synthase (AHAS) and phosphoribosyl anthranilate transferase (PAT). The enzymatic pathways targeted by the novel screening protocols are unique to plants, bacteria and fungi and are present at low levels. Thus, inhibiting these enzymes should present little or no toxicity to humans or animals. The screens provide an efficient and rapid method for assessing the herbicidal potential of test compounds. Lead compounds identified by the novel screening protocols can be used as herbicides to inhibit growth.

  本发明涉及筛选和快速鉴定特异性抑制植物特有的预定酶或代谢靶点或途径的化合物的新方案。新型筛选方法特异或间接影响的酶包括谷氨酰胺合成酶 (GS)、3-脱氧-D-阿拉伯比诺-庚酮酸 7-磷酸合成酶 (DAHP)、二氢二环戊二酸合成酶 (DHPS)、乙酰羟基酸合成酶 (AHAS) 和磷酸核糖基蒽醌转移酶 (PAT)。新型筛选方案所针对的酶途径是植物、细菌和真菌所独有的，而且含量较低。因此，抑制这些酶应该对人类或动物几乎没有毒性。这些筛选为评估试验化合物的除草潜力提供了一种高效、快速的方法。通过新型筛选方案确定的先导化合物可用作抑制生长的除草剂。
• Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
  申请人：Ceres Incorporated

  公开号：EP1033405A2

  公开（公告）日：2000-09-06

  The present invention provides DNA molecules that constitute fragments of the genome of a plant, and polypeptides encoded thereby. The DNA molecules are useful for specifying a gene product in cells, either as a promoter or as a protein coding sequence or as an UTR or as a 3' termination sequence, and are also useful in controlling the behavior of a gene in the chromosome, in controlling the expression of a gene or as tools for genetic mapping, recognizing or isolating identical or related DNA fragments, or identification of a particular individual organism, or for clustering of a group of organisms with a common trait. 0Arabidopsis DNA is used in the present experiment, but the procedure is a general one.

  本发明提供了构成植物基因组片段的 DNA 分子及其编码的多肽。这些 DNA 分子可作为启动子或蛋白质编码序列或 UTR 或 3'终止序列，用于指定细胞中的基因产物，也可用于控制染色体中基因的行为，控制基因的表达，或作为基因绘图、识别或分离相同或相关 DNA 片段、或识别特定生物个体、或对具有共同性状的生物群体进行聚类的工具。 本实验中使用的是拟南芥 DNA，但这是一个通用程序。
• DNA Sequences
  申请人：Ceres Incorporated

  公开号：EP1887081A2

  公开（公告）日：2008-02-13

  The present invention provides DNA molecules that constitute fragments of the genome of a plant, and polypeptides encoded thereby. The DNA molecules are useful for specifying a gene product in cells, either as a promoter or as a protein coding sequence or as an UTR or as a 3' termination sequence, and are also useful in controlling the behavior of a gene in the chromosome, in controlling the expression of a gene or as tools for genetic mapping, recognizing or isolating identical or related DNA fragments, or identification of a particular individual organism, or for clustering of a group of organisms with a common trait.

  本发明提供了构成植物基因组片段的 DNA 分子及其编码的多肽。这些 DNA 分子可作为启动子或蛋白质编码序列或 UTR 或 3'终止序列，用于指定细胞中的基因产物，也可用于控制染色体中基因的行为，控制基因的表达，或作为基因绘图、识别或分离相同或相关 DNA 片段、或识别特定生物个体或具有共同性状的生物群体的工具。
• New genes related to a process for the production of fine chemicals
  申请人：Metanomics GmbH

  公开号：EP1953235A2

  公开（公告）日：2008-08-06

  The present invention relates to a process for the production of the fine chemical in a microorganism, a plant cell, a plant, a plant tissue or in one or more parts thereof. The invention furthermore relates to nucleic acid molecules, polypeptides, nucleic acid constructs, vectors, antisense molecules, antibodies, host cells, plant tissue, propagation material, harvested material, plants, microorganisms as well as agricultural compositions and to their use.

  本发明涉及一种在微生物、植物细胞、植物、植物组织或其一个或多个部分中生产精细化学品的工艺。本发明还涉及核酸分子、多肽、核酸构建体、载体、反义分子、抗体、宿主细胞、植物组织、繁殖材料、收获材料、植物、微生物以及农业组合物及其用途。