2,4,5-trihydroxy-3-methoxy-1,6-hexanedioic acid | 59183-54-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,4,5-trihydroxy-3-methoxy-1,6-hexanedioic acid
• 英文别名: 2,3,5-Trihydroxy-4-methoxyhexanedioic acid；2,3,5-trihydroxy-4-methoxyhexanedioic acid
• CAS: 59183-54-9
• 化学式: C₇H₁₂O₈
• 分子量: 224.167
• InChiKey: MDGDZMIEJCCPTI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  145
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• [EN] ENZYMATIC PRODUCTION OF GLUCARIC ACID FROM GLUCURONIC ACID<br/>[FR] PRODUCTION ENZYMATIQUE D'ACIDE GLUCARIQUE À PARTIR D'ACIDE GLUCURONIQUE
  申请人：GOVERNING COUNCIL UNIV TORONTO

  公开号：WO2020232536A1

  公开（公告）日：2020-11-26

  Described herein are processes and enzymes for the enzymatic production of glucaric acid from glucuronic acid, and more specifically the enzymatic production of substituted glucaric acid from substituted glucuronic acid. Advantageously, the process and enzymes described herein make preferential use substituted glucuronic acid obtained from natural sources, such as underutilized hemicellulose stream from wood and agricultural biorefineries, to produce substantially enantiomerically pure substituted D-glucaric acid.

  本文描述了从葡萄糖醛酸中酶催化生产葡萄糖酸的过程和酶，更具体地说，是从取代葡萄糖醛酸中酶催化生产取代葡萄糖酸。优点在于，本文描述的过程和酶有利地利用从天然来源获得的取代葡萄糖醛酸，例如从木材和农业生物精炼厂的未充分利用的半纤维素流中获得，以生产基本对映纯的取代D-葡萄糖酸。
• ENZYMATIC PRODUCTION OF GLUCARIC ACID FROM GLUCURONIC ACID
  申请人：THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO

  公开号：US20220315957A1

  公开（公告）日：2022-10-06

  Described herein are processes and enzymes for the enzymatic production of glucaric acid from glucuronic acid, and more specifically the enzymatic production of substituted glucaric acid from substituted glucuronic acid. Advantageously, the process and enzymes described herein make preferential use substituted glucuronic acid obtained from natural sources, such as underutilized hemicellulose stream from wood and agricultural biorefineries, to produce substantially enantiomerically pure substituted D-glucaric acid.