6-(2-Hydroxyethyl)oxane-2,3,4,5-tetrol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-(2-Hydroxyethyl)oxane-2,3,4,5-tetrol
• 化学式: C₇H₁₄O₆
• 分子量: 194.18
• InChiKey: DZVQUXRVCGLPJK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.8
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  110
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• [EN] LOW CELL TOXICITY ANTIBIOTIC HYGROMYCIN B<br/>[FR] HYGROMYCINE B ANTIBIOTIQUE PRÉSENTANT UNE FAIBLE TOXICITÉ CELLULAIRE
  申请人：TOKU E COMPANY

  公开号：WO2012122282A1

  公开（公告）日：2012-09-13

  A preparation of antibiotic hygromycin B with low cell toxicity and high purity, and methods of preparing such a preparation, are provided. More specifically, an isolated antibiotic hygromycin B with a purity of greater than 98% and impurities C, D and E individually less than 0.5% and impurity F less than 2%, as measured by HPLC, is described. Uses of this high purity antibiotic hygromycin B include, for example, for in vitro cell selection.