2-(3,5-Dimethoxy-phenoxy)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol | 90-71-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(3,5-Dimethoxy-phenoxy)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
• 英文别名: 3,5-Dimethoxyphenyl hexopyranoside；2-(3,5-dimethoxyphenoxy)-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 90-71-1
• 化学式: C₁₄H₂₀O₈
• 分子量: 316.308
• InChiKey: JDTIMXKVYWJWHE-UHFFFAOYSA-N

物化性质

• 熔点：
  170-170.5°
• 比旋光度：
  D20 -72° (0.12 g/10 ml of aq soln)
• 沸点：
  554.5±50.0 °C(Predicted)
• 密度：
  1.408±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  118
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• Orthomolecular vitamin E derivatives
  申请人：——

  公开号：US20030007961A1

  公开（公告）日：2003-01-09

  Orthomolecular Vitamin E derivative compounds, compositions, and their uses for effecting aging and longevity, nerve activity, hematopoiesis and maintenance of blood cells, hepatic activity, nephritic activity, heart and cardiovascular function, pulmonary function, muscular function, cartilage, bone, and joint health, gastrointestinal function, reproductive system function, vision, immune function, cell membrane integrity, and pain and inflammation; preventing or treating diseases or conditions; treating cancers or obesity; and reducing the risk of Sudden Infant Death Syndrome in an animal. The compounds of the present invention are of formula I: 1 or a pharmaceutically acceptable salt, ester, or solvate, thereof, wherein: A, B, C, D, and R are as defined herein.

  正分子维生素 E 衍生物化合物、组合物及其在以下方面的用途：衰老和长寿、神经活动、造血和血细胞维护、肝活动、肾活动、心脏和心血管功能、肺功能、肌肉功能、软骨、骨骼和关节健康、肠胃功能、生殖系统功能、视力、免疫功能、细胞膜完整性以及疼痛和炎症；预防或治疗疾病或病症；治疗癌症或肥胖症；降低动物患婴儿猝死综合征的风险。本发明的化合物如式 I 所示： 1 或其药学上可接受的盐、酯或溶液，其中： A、B、C、D 和 R 如本文所定义。
• Orthomolecular sulpho-adenosylmethionine derivatives with antioxidant properties
  申请人：——

  公开号：US20030078231A1

  公开（公告）日：2003-04-24

  Orthomolecular Sulpho-Adenosylmethionine derivative compounds, compositions, and their uses for effecting a biological activity in an animal, such as neurochemical activity; liver biology activity; heart and artery function; cartilage, bone and joint health; stomach and/or intestinal lining resistance to ulceration; immune function; cell membrane integrity; and pain and inflammation. The compounds of the present invention are further useful for preventing or treating diseases or conditions; treating viral infections, infectious diseases, leukemia, and obesity; and reducing the risk of Sudden Infant Death Syndrome in an animal. The compounds of the present invention are of formula I: 1 A is 0 or N; and X is a reaction product as defined herein.

  本发明的正分子磺基腺苷蛋氨酸衍生物化合物、组合物及其用途可影响动物的生物活性，如神经化学活性；肝脏生物活性；心脏和动脉功能；软骨、骨骼和关节健康；胃和/或肠壁抗溃疡能力；免疫功能；细胞膜完整性；以及疼痛和炎症。本发明的化合物还可用于预防或治疗疾病或病症；治疗病毒感染、传染病、白血病和肥胖症；降低动物患婴儿猝死综合症的风险。本发明的化合物如式 I 所示： 1 A 是 0 或 N；以及 X 是本文定义的反应产物。
• Composition cosmétique contenant du phloroglucinol
  申请人：L'OREAL

  公开号：EP0931542B1

  公开（公告）日：2004-01-14
• COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS
  申请人：Washington University

  公开号：US20210171563A1

  公开（公告）日：2021-06-10

  The present invention is directed to various compounds, compositions, and methods for treating bacterial infections such as urinary tract infections.
• US6054137A
  申请人：——

  公开号：US6054137A

  公开（公告）日：2000-04-25