4-Hydroxy-6-[2-(2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl]oxan-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 4-Hydroxy-6-[2-(2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl]oxan-2-one
• 化学式: C₁₈H₂₆O₃
• 分子量: 290.4
• InChiKey: NXIASLUNMKAUTN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3,5-dihydroxy-7-(2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoic acid 生成 4-Hydroxy-6-[2-(2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl]oxan-2-one
  参考文献：
  名称：

  TEHRAXARA, AKIRA;KITAMI, MAKOTO;FUKADZAVA, JOSIMI

  摘要：

  DOI：

文献信息

• ANTIEPILEPTIC, HYPOCHOLESTEROLEMIC AND NEUROPROTECTIVE COMPOUND
  申请人：Burgos Muñoz Javier Santos

  公开号：US20120095091A1

  公开（公告）日：2012-04-19

  The present invention describes a compound of formula (I) its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of the compound and of its hydroxy acid form and, in particular, said compound, its hydroxy acid form, salts, etc. for its use in the prevention of: neurodegenerative diseases, cognitive deterioration, diseases associated with undesired oxidation, age-associated pathological processes and progeria, epilepsy, epileptic seizures and convulsions, cardiovascular diseases such as atherosclerosis, atrial fibrillation, dyslipemia, hypercholesterolemia, hyperlipidemia, and hypertriglyceridemia, or fungal or viral infections.