4-methyl-3-octanone | 6137-15-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-methyl-3-octanone
• 英文别名: 4-methyl-octan-3-one；4-Methyl-octan-3-on；4-Methyloctan-3-one
• CAS: 6137-15-1
• 化学式: C₉H₁₈O
• 分子量: 142.241
• InChiKey: NXWYGZOSQBYIAH-UHFFFAOYSA-N

物化性质

• 沸点：
  180.0±8.0 °C(Predicted)
• 密度：
  0.814±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 镍 作用下， 生成 4-methyl-3-octanone
  参考文献：
  名称：

  Dubois; Luft, Bulletin de la Societe Chimique de France, 1954, p. 1153

  摘要：

  DOI：

文献信息

• Method for Asymmetric Hydrosilylation of Ketones
  申请人：Chan Albert Sun-Chi

  公开号：US20080269490A1

  公开（公告）日：2008-10-30

  Method of asymmetrically hydrosilylating substrates using catalysts having a ligand of the compound of the formula (I) wherein R is optionally substituted alkyl, cycloalkyl, aryl or heteroaryl; R′ is hydrogen, optionally substituted lower alkyl; and R″ is hydrogen, halogen, optionally substituted alkyl, hydroxy, amino (e.g., primary, secondary or tertiary), alkenyl; or an enantiomer thereof; or an enantiomeric mixture thereof with a transition metal. Particularly suitable reactions include the asymmetric hydrosilylation of ketones.

  使用具有化合物公式(I)的配体的催化剂不对称地对底物进行氢硅烷化的方法 其中 R是可选择地取代的烷基、环烷基、芳基或杂环芳基; R′是氢、可选择地取代的较低烷基; 和 R″是氢、卤素、可选择地取代的烷基、羟基、氨基(例如，一级、二级或三级)、烯基; 或其对映体; 或其与过渡金属的对映混合物。特别适合的反应包括酮的不对称氢硅烷化。
• A PROCESS FOR THE PRODUCTION OF A MIXTURE COMPRISING CYCLOHEXANOL AND CYCLOHEXANONE
  申请人：CAP III B.V.

  公开号：EP3115350A1

  公开（公告）日：2017-01-11

  A continuous process for the production of a mixture comprising cyclohexanone and cyclohexanol by hydrogenation of phenol, which process is performed in a multi-tubular reactor, characterised in that said multi-tubular reactor has been used for the dehydrogenation of cyclohexanol; a chemical plant suitable for the hydrogenation of phenol comprising a multi-tubular reactor; cyclohexanone prepared in a chemical plant comprising a multi-tubular reactor; and a process for constructing such a plant.

  一种通过苯酚氢化生产由环己酮和环己醇组成的混合物的连续工艺，该工艺在多管式反应器中进行，其特征在于所述多管式反应器用于环己醇的脱氢；一种适用于苯酚氢化的化工装置，包括一个多管式反应器；在包括一个多管式反应器的化工装置中制备的环己酮；以及建造这种装置的工艺。
• A PROCESS FOR THE PRODUCTION OF A MIXTURE COMPRISING CYCLOHEXANONE AND CYCLOHEXANOL
  申请人：CAP III B.V.

  公开号：EP3095774A1

  公开（公告）日：2016-11-23

  A continuous process for the production of a mixture comprising cyclohexanone and cyclohexanol by hydrogenation of phenol, which process is performed in a chemical plant comprising a multi-tubular reactor characterised in that said multi-tubular reactor has been used for the hydrogenation of benzene; a chemical plant suitable for the hydrogenation of phenol comprising a multi-tubular reactor; cyclohexanone prepared in a chemical plant comprising a multi-tubular reactor; and a process for constructing such a plant.

  一种通过苯酚氢化生产由环己酮和环己醇组成的混合物的连续工艺，该工艺在一个包括多管式反应器的化工装置中进行，其特征在于所述多管式反应器曾用于苯的氢化；一种适用于苯酚氢化的化工装置，包括一个多管式反应器；在一个包括多管式反应器的化工装置中制备环己酮；以及一种建造这种装置的工艺。
• Process for revamping a plant for the production of cyclohexanone
  申请人：CAP III B.V.

  公开号：US10130895B2

  公开（公告）日：2018-11-20

  A process for the construction of a second chemical plant, which second chemical plant is suitable for the separation of cyclohexanone from a second mixture, which second mixture comprises reaction products from the hydrogenation of phenol. The process comprises providing a first chemical plant, which first chemical plant is suitable for the separation of cyclohexanone from a first mixture, and a second chemical plant comprising a distillation column suitable for distilling overhead cyclohexanone reused from the first chemical plant.

  一种建造第二化工厂的工艺，该第二化工厂适用于从第二混合物中分离环己酮，该第二混合物包括苯酚氢化反应产物。该工艺包括提供一个第一化学工厂，该第一化学工厂适用于从第一混合物中分离环己酮；以及一个第二化学工厂，该第二化学工厂包括一个蒸馏塔，该蒸馏塔适用于蒸馏从第一化学工厂重复使用的架空环己酮。
• Taguchi, Kazuhiko; Nakagawa, Hideto; Hirabayashi, Tomotaka, Journal of the American Chemical Society, 2004, vol. 126, # 1, p. 72 - 73
  作者：Taguchi, Kazuhiko、Nakagawa, Hideto、Hirabayashi, Tomotaka、Sakaguchi, Satoshi、Ishii, Yasutaka

  DOI：——

  日期：——