HexNAc-Hex

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: HexNAc-Hex
• 英文别名: N-[2,5-dihydroxy-6-(hydroxymethyl)-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-3-yl]acetamide
• 化学式: C₁₄H₂₅NO₁₁
• 分子量: 383.35
• InChiKey: HMQPEDMEOBLSQB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  198
• 氢给体数：
  8
• 氢受体数：
  11

文献信息

• LIPID A AND OTHER CARBOHYDRATE LIGAND ANALOGS
  申请人：Oncothyreon Inc.

  公开号：EP1549322B1

  公开（公告）日：2010-02-17
• [EN] METHODS FOR ENRICHING MESENCHYMAL STEM CELLS<br/>[FR] MÉTHODES POUR ENRICHIR DES CELLULES SOUCHES MÉSENCHYMATEUSES
  申请人：AGENCY SCIENCE TECH & RES

  公开号：WO2019045649A1

  公开（公告）日：2019-03-07

  Methods of enriching non-senescent mesenchymal stem cells (MSCs) and methods of performing quality control for non-senescent MSCs are disclosed. The methods comprise contacting a sample comprising MSCs with a probe (specifically peanut agglutinin, PNA) that binds to a glycan (specifically glycan T-antigen) expressed on the surface of MSCs, with the separation or determination of non-senescent MSCs from senescent MSCs based on a difference in expression of the glycan at the cell surface, i.e. the non-senescent MSCs express more of the glycan than senescent MSCs. A high amount of non-senescent MSCs is indicative of a sample of acceptable quality.