4'-(3,7-dimethyl-octa-2,6-dienyl)-stilbene-2,4,3',5'-tetraol | 537-41-7

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 4'-(3,7-dimethyl-octa-2,6-dienyl)-stilbene-2,4,3',5'-tetraol
• 英文别名: 3.5.2'.4'-Tetrahydroxy-4-(3.7-dimethyl-octadien-(2.6)-yl)-stilben；4-(3.7-Dimethyl-octadien-(2.6)-yl)-stilbentetrol-(3.5.2'.4')；4'-(3,7-Dimethyl-octa-2,6-dienyl)-stilben-2,4,3',5'-tetraol；Chlorophorin；2,4,3',5'-Tetrahydroxy-4'(3,7-di-methyl-2,6-octadienyl)-stilbene；5-[2-(2,4-dihydroxyphenyl)ethenyl]-2-(3,7-dimethylocta-2,6-dienyl)benzene-1,3-diol
• CAS: 537-41-7
• 化学式: C₂₄H₂₈O₄
• 分子量: 380.484
• InChiKey: OEILZVSHVTYHKL-UHFFFAOYSA-N

物化性质

• 沸点：
  614.0±55.0 °C(Predicted)
• 密度：
  1.196±0.06 g/cm3(Predicted)
• LogP：
  6.145 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  80.9
• 氢给体数：
  4
• 氢受体数：
  4

制备方法与用途

氯化酚是一种 melanocortin 受体的抑制剂。它能降低 B16F10 黑色素瘤细胞中酪氨酸酶的活性，并抑制 α-黑素细胞刺激激素引起的黑色素生成。

反应信息

• 作为反应物：
  描述：

  4'-(3,7-dimethyl-octa-2,6-dienyl)-stilbene-2,4,3',5'-tetraol 在 氯仿 、 臭氧 作用下， 生成 4-carboxymethyl-3,5-dihydroxy-benzoic acid
  参考文献：
  名称：

  Combined extraction of high spatial resolution wind speed and wind direction from SAR images: A new approach using wavelet transform

  摘要：

  Low spatial resolution wind extraction from scatterometer data has reached an operational status and the results are widely used in global-scale meteorological models. A new need is emerging concerning high spatial resolution wind fields extraction for the offshore industry. This need can be managed using high spatial resolution data, such as those from synthetic aperture radar (SAR) sensors. This paper presents a combined wind parameters extraction algorithm at high spatial resolution from a single SAR image. This algorithm makes use of advanced signal-processing tools. The results are compared with in situ data and future prospects are presented.

  DOI：

  10.5589/m02-038

文献信息

• METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE
  申请人：Moazed Kambiz Thomas

  公开号：US20110280909A1

  公开（公告）日：2011-11-17

  Methods and systems are described for a rapid and sustainable change in the pigment melanin content of melanocytes of the iris stroma, thereby to change the color of the eye. Also described are nanoparticle compositions for lightening the pigmented tissues or treating a pigmented tissue related disease.

  描述了一种快速和可持续改变虹膜基质黑色素含量的黑色素细胞的方法和系统，从而改变眼睛的颜色。还描述了用于淡化有色组织或治疗有色组织相关疾病的纳米颗粒组合物。
• Observations and Model Simulations of Carbon Monoxide Emission Factors from a California Highway
  作者：Anthony E. Held、Daniel P.Y. Chang、Debbie A. Niemeier

  DOI：10.1080/10473289.2001.10464248

  日期：2001.1

  A series of twelve intensively monitored 1-hr CO dispersion studies were conducted near Davis, CA, in winter 1996. The experimental equipment included twelve CO sampling ports at elevations up to 50 m, three sonic anemometers, a tethersonde station, aircraft measurements of wind and temperature profile aloft, and a variety of conventional meteorological equipment. The study was designed to explore the role of vehicular exhaust buoyancy during worst-case meteorological conditions, such as low winds oriented in near-parallel alignment with the road during a surface-based nocturnal inversion. From the study, field estimates of the CO emission factor (EF) from a California vehicle fleet were computed using two different methods. The analysis suggests that the CT-EMFAC/EMFAC (EMission FACtor) models currently used to conduct federal conformity modeling significantly overpredict CO emissions for high-speed, free-flowing traffic on California highways.
• [EN] METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE<br/>[FR] PROCÉDÉ ET SYSTÈME DE RÉALISATION DE MODIFICATIONS DANS UN TISSU PIGMENTÉ
  申请人：MOAZED KAMBIZ THOMAS

  公开号：WO2010087983A1

  公开（公告）日：2010-08-05

  Methods and systems are described for a rapid and sustainable change in the pigment melanin content of melanocytes of the iris stroma, thereby to change the color of the eye. Also described are nanoparticle compositions for lightening the pigmented tissues or treating a pigmented tissue related disease.
• [EN] METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE<br/>[FR] PROCÉDÉ ET SYSTÈME POUR RÉALISER DES MODIFICATIONS DANS UN TISSU PIGMENTÉ
  申请人：MOAZED KAMBIZ THOMAS

  公开号：WO2011011065A1

  公开（公告）日：2011-01-27

  Methods and systems are described for a rapid and sustainable change in the pigment melanin content of melanocytes of the iris stroma, thereby to change the color of the eye. Also described are nanoparticle compositions for lightening the pigmented tissues or treating a pigmented tissue related disease.