2,3,4-Trihydroxy-5-(hydroxymethyl)cyclohexan-1-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3,4-Trihydroxy-5-(hydroxymethyl)cyclohexan-1-one
• 化学式: C₇H₁₂O₅
• 分子量: 176.17
• InChiKey: ACVTTWBZLGNMCH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  98
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• Conjugates containing hydrophilic spacer linkers
  申请人：Endocyte, Inc.

  公开号：US10738086B2

  公开（公告）日：2020-08-11

  Described herein are compositions and methods for use in targeted drug delivery using cell-surface receptor binding drug delivery conjugates containing hydrophilic spacer linkers for use in treating disease states caused by pathogenic cell populations.

  本文描述了使用含有亲水间隔连接体的细胞表面受体结合给药共轭物进行靶向给药的组合物和方法，用于治疗由致病细胞群引起的疾病状态。
• Conjugates Containing Hydrophilic Spacer Linkers
  申请人：Endocyte, Inc.

  公开号：US20170151340A1

  公开（公告）日：2017-06-01

  Described herein are compositions and methods for use in targeted drug delivery using cell receptor binding drug delivery conjugates containing hydrophilic spacer linkers for use in imaging, diagnosing, and/or treating diseases and disease states caused by pathogenic cell populations.