6-Phospho-gluconsaeure | 547753-94-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-Phospho-gluconsaeure
• 英文别名: d-Gluconic acid, 6-(dihydrogen phosphate), trisodium salt；2,3,4,5-tetrahydroxy-6-phosphonooxyhexanoic acid
• CAS: 547753-94-6
• 化学式: C₆H₁₃O₁₀P
• 分子量: 276.137
• InChiKey: BIRSGZKFKXLSJQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.5
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  185
• 氢给体数：
  7
• 氢受体数：
  10

文献信息

• Compositions and methods of PGL for the increased production of isoprene
  申请人：Danisco US Inc.

  公开号：EP2857518A2

  公开（公告）日：2015-04-08

  Provided herein are improved compositions and methods for the increased production of isoprene. Also provided herein are improved compositions and methods for the increased production of heterologous polypeptides capable of biological activity.

  本文提供了提高异戊二烯产量的改良组合物和方法。本文还提供了提高具有生物活性的异源多肽产量的改良组合物和方法。
• DRUG DELIVERY SYSTEM USING SOLUTION
  申请人：Kyoto University

  公开号：EP3888693A1

  公开（公告）日：2021-10-06

  The present invention provides a means excellent in efficiency of introduction of a nucleic acid, a protein, a complex thereof, or the like into cells, in particular a method using a solution for transduction. In the method for transducing a molecule(s) of interest into a cell according to the present invention, comprising a step of contacting the cell with the molecule(s) of interest and a solution for transduction according to the present invention, the solution for transduction contains: at least one of the following (A1) to (A5); and (B) a salt: (A1) a compound represented by formula (I) excluding a predetermined compound, or a salt thereof; (A2) a compound represented by formula (II), or a salt thereof; (A3) a nucleic-acid base or the like, or a salt thereof; (A4) a compound represented by formula (III), or a salt thereof, excluding malic acid; and (A5) at least one selected from the group consisting of creatinine, hydroxyproline, 1,3-butanediol, trientine, D-cellobiose, 1,3-dimethylurea, pantolactone and trimethadione, or a salt thereof.

  本发明提供了一种将核酸、蛋白质、其复合物或类似物高效导入细胞的方法，特别是一种使用转导溶液的方法。在根据本发明的将感兴趣的分子转导到细胞中的方法中，包括将细胞与感兴趣的分子和根据本发明的转导用溶液接触的步骤，转导用溶液包含：以下(A1)至(A5)中的至少一种；和(B)一种盐：(A1)式(I)代表的化合物，不包括预定化合物，或其盐； (A2)式(II)代表的化合物，或其盐； (A3)核酸碱或类似物，或其盐；(A4) 由式（III）代表的化合物，或其盐，不包括苹果酸；以及 (A5) 至少一种选自肌酸酐、羟脯氨酸、1,3-丁二醇、三戊二酸、D-纤维二糖、1,3-二甲基脲、泛醇内酯和三甲二酮组成的组，或其盐。
• COMPOSITIONS AND METHODS OF PGL FOR THE INCREASED PRODUCTION OF ISOPRENE
  申请人：Danisco US Inc.

  公开号：EP2516654A2

  公开（公告）日：2012-10-31
• COMPOSITIONS AND METHODS FOR THE INCREASED PRODUCTION OF ISOPRENE WITH 6-PHOSPHOGLUCONOLACTONASE (PGL)
  申请人：Danisco US Inc.

  公开号：EP2516654B1

  公开（公告）日：2015-01-21
• PENTOSE PHOSPHATE PATHWAY UPREGULATION TO INCREASE PRODUCTION OF NON-NATIVE PRODUCTS OF INTEREST IN TRANSGENIC MICROORGANISMS
  申请人：E.I. Du Pont De Nemours And Company

  公开号：EP2553107A2

  公开（公告）日：2013-02-06