6-[2-(2,6-Dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl]-4-hydroxyoxan-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 6-[2-(2,6-Dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl]-4-hydroxyoxan-2-one
• 化学式: C₁₉H₂₈O₃
• 分子量: 304.4
• InChiKey: BKZPCUPKVCPRQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.74
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Compound Separated from Monascus-Fermented Rice,The Preparation Method and Uses Thereof
  申请人：Duan Zhenwen

  公开号：US20130310450A1

  公开（公告）日：2013-11-21

  The present invention discloses a compound separated from Monascus -fermented rice, the preparation method and uses thereof. Specifically, the present invention discloses a compound represented by the Formula I, or a pharmaceutically acceptable salt thereof, wherein, R 1 is selected from the group consisting of hydrogen, hydroxyl, C 1-6 straight or branched alkoxyl, (II), (III) and (IV); R 2 is hydrogen or C 1-6 alkyl; R 3 is selected from the group consisting of hydrogen, hydroxyl and C 1-6 straight or branched alkoxyl. The present invention further discloses a pharmaceutical composition containing the compound. The compound of the present invention has HMG-CoA reductase inhibition effects.
• US9371304B2
  申请人：——

  公开号：US9371304B2

  公开（公告）日：2016-06-21