摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词

4-Oxo-4-(3-pyridyl)-butanamide | 61192-49-2

中文名称
——
中文别名
——
英文名称
4-Oxo-4-(3-pyridyl)-butanamide
英文别名
4-oxo-4-pyridin-3-ylbutanamide
4-Oxo-4-(3-pyridyl)-butanamide化学式
CAS
61192-49-2
化学式
C9H10N2O2
mdl
——
分子量
178.19
InChiKey
DJEKVKGYYASXCW-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    -0.8
  • 重原子数:
    13
  • 可旋转键数:
    4
  • 环数:
    1.0
  • sp3杂化的碳原子比例:
    0.22
  • 拓扑面积:
    73
  • 氢给体数:
    1
  • 氢受体数:
    3

ADMET

代谢
4-氧代-4-(3-吡啶基)-丁酰胺是已知尼古丁的第三手烟雾代谢物。
4-Oxo-4-(3-pyridyl)-butanamide is a known thirdhand smoke metabolite of Nicotine.
来源:NORMAN Suspect List Exchange

文献信息

  • [EN] MACROLIDE ANTIBIOTICS<br/>[FR] ANTIBIOTIQUES A BASE DE MACROLIDES
    申请人:GLAXO GROUP LTD
    公开号:WO2002050091A1
    公开(公告)日:2002-06-27
    The present invention relates to 11,12 η lactone ketolides of formula (I) wherein R, R?1, R2, R3¿ are as defined herein and pharmaceutically acceptable salts and solvates thereof, to process for their preparation and their use in therapy or prophylaxis of systemic or topical bacterial infections in a human or animal body.
    本发明涉及式(I)的11,12-η内酯酮类化合物,其中R,R?1,R2,R3¿如本文所定义,并且其药学上可接受的盐和溶剂合物,以及其制备过程和在治疗或预防人类或动物体内的全身性或局部细菌感染中的应用。
  • Macrolide antibiotics
    申请人:——
    公开号:US20040077557A1
    公开(公告)日:2004-04-22
    The present invention relates to 11,12 &ggr; lactone ketolides of formula (I) wherein R, R 1 , R 2 , R 3 are as defined herein and pharmaceutically acceptable salts and solvates thereof, to process for their preparation and their use in therapy or prophylaxis of systemic or topical bacterial infections in a human or animal body.
    本发明涉及公式(I)中的11,12 &ggr;内酯酮类化合物,其中R、R1、R2、R3如本文所定义的,以及其药学上可接受的盐和溶剂化物,以及它们的制备方法及在人或动物体内治疗或预防全身或局部细菌感染中的应用。
  • Macrolide Antibiotics
    申请人:ALIHODZIC Sulejman
    公开号:US20060211636A1
    公开(公告)日:2006-09-21
    The present invention relates to 11,12 γ lactone ketolides of formula (I) wherein R, R 1 , R 2 , R 3 are as defined herein and pharmaceutically acceptable salts and solvates thereof, to process for their preparation and their use in therapy or prophylaxis of systemic or topical bacterial infections in a human or animal body.
    本发明涉及式(I)的11,12-γ内酯酮类化合物,其中R、R1、R2、R3如定义所述,以及其药学上可接受的盐和溶剂化物,以及其制备方法和在人或动物体内治疗或预防系统性或局部细菌感染的用途。
  • Biological control in electronic smoking articles
    申请人:PHILIP MORRIS PRODUCTS S.A.
    公开号:US10687556B2
    公开(公告)日:2020-06-23
    A smoking article includes a housing having a mouthpiece and configured to receive a nicotine-containing aerosol generating substance. The smoking article also includes control electronics configured to control delivery of an amount of nicotine-containing aerosol from the nicotine-containing aerosol generating substrate through the mouthpiece. The smoking article further includes a nicotine metabolite sensor positioned at the mouth piece and operably coupled to the control electronics. The sensor is positioned such that when a smoker places their lips in contact with the mouthpiece the sensor can detect an amount or concentration of a nicotine metabolite in the smoker's saliva. The smoking article can store or report data regarding the amount of nicotine metabolite detected by the sensor to, for example, the smoker. In addition or alternatively, the control electronics can receive data from the sensor to control whether the amount of the nicotine-containing aerosol is delivered.
    一种烟具包括一个外壳,外壳上有一个吹嘴,配置成接收含尼古丁气溶胶生成物质。该烟具还包括控制电子装置,其配置用于控制从含尼古丁气溶胶产生基质通过口罩输送一定量的含尼古丁气溶胶。该烟具还包括一个尼古丁代谢物传感器,该传感器位于口罩处并与控制电子装置可操作地耦合。传感器的位置使得当吸烟者将嘴唇与口罩接触时,传感器可以检测到吸烟者唾液中尼古丁代谢物的数量或浓度。烟具可以存储或向吸烟者等报告传感器检测到的尼古丁代谢物的量。此外,控制电子装置还可以接收来自传感器的数据,以控制含尼古丁气雾剂的输送量。
  • MACROLIDE ANTIBIOTICS
    申请人:GLAXO GROUP LIMITED
    公开号:EP1363925A1
    公开(公告)日:2003-11-26
查看更多