N-(1,3,4-trihydroxyoctadecan-2-yl)hexacosanamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-(1,3,4-trihydroxyoctadecan-2-yl)hexacosanamide
• 化学式: C₄₄H₈₉NO₄
• 分子量: 696.2
• InChiKey: GKRXVCWVXYHWOD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  17.6
• 重原子数：
  49
• 可旋转键数：
  41
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.98
• 拓扑面积：
  89.8
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• Method for Evaluating Health of Skin
  申请人：KAO CORPORATION

  公开号：US20190302133A1

  公开（公告）日：2019-10-03

  A method of evaluating the health of skin, containing the steps of: preparing a lipid sample from a collected sample of a stratum corneum of a test subject; quantitatively determining respective contents of one kind of ceramide component A and one kind of ceramide component B included in the prepared lipid sample prepared from a collected sample of a stratum corneum of the test subject; calculating the content ratio of the quantitatively determined content of the ceramide component A to the quantitatively determined content of the ceramide component B; and evaluating the health of the skin of the test subject from the calculated content ratio; wherein the ceramide component A is selected from the group consisting of a non-hydroxyacyl-phytosphingosine ceramide, a non-hydroxyacyl-6-hydroxysphingosine ceramide component, an esterified ω-hydroxyacyl-6-hydroxysphingosine ceramide component and an esterified ω-hydroxyacyl-phytosphingosine ceramide component; and the ceramide component B is selected from the group consisting of a non-hydroxyacyl-sphingosine ceramide and an α-hydroxyacyl-sphingosine ceramide component.