4-Acetylphenyl hexopyranoside

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-Acetylphenyl hexopyranoside
• 英文别名: 1-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]ethanone
• 化学式: C₁₄H₁₈O₇
• 分子量: 298.29
• InChiKey: GOZCEKPKECLKNO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  116
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• A method of producing a low molecular weight organic compound in a cell
  申请人：Poalis A/S

  公开号：EP1510586A1

  公开（公告）日：2005-03-02

  A method of producing a low molecular weight organic compound (e.g. a plant or bacteria secondary metabolite) in increased yields involving use of a cell (e.g. a plant or microorganism cell), which comprises a gene involved in the biosynthesis pathway leading to a low molecular weight organic aglycon compound and a glycosyltransferase gene capable of glycosylating the produced aglycon.

  一种提高低分子量有机化合物（如植物或细菌的次级代谢产物）产量的方法，涉及使用细胞（如植物或微生物细胞），该细胞包括一个参与导致低分子量有机苷元化合物的生物合成途径的基因和一个能够将所产生的苷元糖基化的糖基转移酶基因。
• Hydrosoluble [6)-O-alpha-d-glcp-(1->]n-6-o-bêta-d-glcp-(1->-phenllic derivatives with dermocosmetic, nutritional and therapeutic applications, and compositions containing said water soluble compounds
  申请人：Libragen

  公开号：EP2202237A1

  公开（公告）日：2010-06-30

  The invention relates to [6)-O-α-D-Glcp-(1→]n-6-O-β-D-Glcp-(1→-phenolic derivatives. These [6)-O-α-D-Glcp-(1→]n-6-O-β-D-Glcp-(1→phenolic derivatives of selected phenolics are new, have a solubility in water higher than that of their parent O-β-D-Glcp-(1→-phenolic derivatives and have useful applications in cosmetic, nutrition and pharmaceutical compositions, such as treating or preventing oxidative stress, a cancer, a cardiovascular disease, a bacterial infection, a viral infection, a fungal infection, a UV-induced erythema, an allergy, a metabolism disorder, diabetes, an obesity, an hormonal disorder, a bone disease, a pain, a brain disease, a mouth or teeth disease, an inflammatory or immune disorder.

  本发明涉及[6)-O-α-D-谷氨酰-(1→]n-6-O-β-D-谷氨酰-(1→酚类衍生物。这些[6)-O-α-D-Glcp-(1→]n-6-O-β-D-Glcp-(1→酚类衍生物是新的，在水中的溶解度高于其母体 O-β-D-Glcp-(1→酚类衍生物的溶解度，在化妆品、营养品和药物组合物中具有有用的应用，如治疗或预防氧化应激、癌症、心血管疾病、细菌感染、病毒感染、真菌感染、紫外线引起的红斑、过敏、代谢紊乱、糖尿病、肥胖症、荷尔蒙紊乱、骨病、疼痛、脑部疾病、口腔或牙齿疾病、炎症或免疫紊乱。
• NATURAL BIOLOGICAL EXTRACTS OBTAINABLE BY EXTRACTION WITH EUTECTICAL SOLVENTS
  申请人：Naturex

  公开号：EP3704956A1

  公开（公告）日：2020-09-09

  A natural biological liquid extract comprising plant (e.g. vegetable) and/or animal and/or prokaryotic biological material obtained by the extraction method, wherein the method comprises the following steps: a. immersing, while stirring, a ground or unground biological material in a solvent, wherein the solvent is a clear, stable and fluid mixture comprising: (i) betaine (trimethyl glycine) or a hydrated form of betaine; (ii) at least one hydrogen bond donor compound selected from the group consisting of polyols and organic acids; and (iii) water; wherein the ratio of betaine or a hydrated form of betaine to the at least one hydrogen bond donor is from 1:1.5 to 1:3 and the proportion of water added to the mixture is from 15 to 30% by weight; with the proviso that the eutectic extraction solvent does not contain any exogenous sugar and/or amine salt and/or anion; b. macerating or percolating or infusing the mixture obtained in step a. at a temperature between 20 and 60°C; then c. filtering the extraction product obtained at b., thereby obtaining a natural biological liquid extract derived from the plant (e.g. vegetable) and/or animal and/or prokaryotic biological material.

  一种天然生物液体提取物，包括通过提取方法获得的植物（如蔬菜）和/或动物和/或原核生物材料，其中该方法包括以下步骤： a. 在搅拌的同时，将磨碎或未磨碎的生物材料浸入溶剂中，其中溶剂为透明、稳定的流体混合物，包括 (i) 甜菜碱（三甲基甘氨酸）或水合形式的甜菜碱； (ii) 至少一种选自多元醇和有机酸的氢键供体化合物；以及 (iii) 水； 其中甜菜碱或甜菜碱的水合形式与至少一种氢键供体的比例为 1:1.5 至 1:3，加入混合物中的水的比例为 15%至 30%（按重量计）； 但共晶萃取溶剂不含任何外源糖和/或胺盐和/或阴离子； b. 将步骤 a 中得到的混合物在 20 至 60°C 的温度下浸渍、渗滤或灌注；然后 c. 过滤 b.步骤中得到的提取物，从而得到从植物（如蔬菜）和/或动物和/或原核生物材料中提取的天然生物液体提取物。
• Eutectic extraction solvents, extraction methods by eutectigenesis using said solvents, and extracts derived from said extraction methods
  申请人：NATUREX

  公开号：US10960042B2

  公开（公告）日：2021-03-30

  A eutectic extraction solvent for extracting plant (e.g. vegetable) and/or animal and/or prokaryotic biological material, wherein the solvent is a clear, stable and fluid mixture comprising: (a) betaine or a hydrated form of betaine; (b) at least one hydrogen bond donor compound selected from the group consisting of polyols and organic acids; and (c) water with the proviso that the eutectic extraction solvent does not contain any exogenous sugar and/or amine salt and/or anion.

  一种共晶萃取溶剂，用于萃取植物（如蔬菜）和/或动物和/或原核生物材料，其中溶剂为透明、稳定的流体混合物，包括：(a)甜菜碱或甜菜碱的水合形式；(b)至少一种选自多元醇和有机酸组成的组的氢键供体化合物；(c)水，但共晶萃取溶剂不含任何外源糖和/或胺盐和/或阴离子。
• Process for the isolation of a major harmful oxidant from cigarette smoke
  申请人：Council of Science and Industrial Research

  公开号：US20030111087A1

  公开（公告）日：2003-06-19

  The components of cigarette smoke, known until now, do not explain the overwhelming hazardous effects of smoking; this invention describes the isolation, identification and procedures for determination of the structure, properties and assay of a relatively stable major harmful oxidant (cs-oxidant) present in the cigarette smoke, the content of which is about 190±10 &mgr;g per cigarette; the cs-oxidant alone almost quantitatively accounts for the oxidative damage of proteins produced by the aqueous extract of whole cigarette smoke, it is also responsible for the oxidative damage of DNA; since the cs-oxidant is relatively stable, it further explains the deleterious effects of the side stream smoke and passive smoking; a number of chemical compounds/agents including vitamin C have been found to prevent the cs-oxidant induced protein oxidation in vitro.

  本发明描述了香烟烟雾中存在的一种相对稳定的主要有害氧化剂（cs-氧化剂）的分离、鉴定和测定其结构、性质和化验的程序，该氧化剂的含量约为每支香烟 190±10 微克；由于 cs-氧化剂相对稳定，它进一步解释了侧流烟雾和被动吸烟的有害影响；已发现包括维生素 C 在内的一些化合物/试剂可在体外防止 cs-氧化剂诱导的蛋白质氧化。