Anhydrid von myo-Inosit. | 846569-28-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Anhydrid von myo-Inosit.
• 英文别名: 2-Deoxyinosose；2,3,4,5-tetrahydroxycyclohexan-1-one
• CAS: 846569-28-6
• 化学式: C₆H₁₀O₅
• 分子量: 162.142
• InChiKey: GZYCZKBRQBKGJW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.7
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  98
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• [EN] PROCESSES FOR THE PURIFICATION OF VOGLIBOSE AND INTERMEDIATES THEREOF<br/>[FR] PROCEDES POUR LA PURIFICATION DE LA VOGLIBOSE ET DE SES INTERMEDIAIRES
  申请人：RANBAXY LAB LTD

  公开号：WO2005092834A1

  公开（公告）日：2005-10-06

  Processes for the purification of voglibose are provided. Also provided are processes for the purification of substituted or unsubstituted 5-oxo-1,2,3,4-cyclohexanetetrol and substituted 5-amino-1,2,3,4-cyclohexanetetrol, which compounds are useful intermediates in the preparation of voglibose.

  提供了用于净化伏格列波糖的工艺。还提供了用于净化取代或未取代的5-氧代-1,2,3,4-环己烷四醇和取代的5-氨基-1,2,3,4-环己烷四醇的工艺，这些化合物是伏格列波糖制备中有用的中间体。
• [EN] PROCESS FOR THE PREPARATION OF 1,2,3,4-CYCLOHEXANETETROL DERIVATIVES<br/>[FR] PROCEDE POUR LA PREPARATION DE DERIVES DE 1,2,3,4-CYCLOHEXANETETROL
  申请人：RANBAXY LAB LTD

  公开号：WO2005049547A1

  公开（公告）日：2005-06-02

  Provided herein are processes for the preparation of 1,2,3,4-cyclohexanetetrol derivatives, which are useful intermediates for the synthesis of voglibose; processes for the preparation of substituted 2,3,4,5-tetrahydroxycyclohexanone; and processes for preparing voglibose. Also provided are compounds formed by such processes.

  本文提供了制备1,2,3,4-环己烷四醇衍生物的方法，这些衍生物是合成沃格利波糖的有用中间体；制备取代的2,3,4,5-四羟基环己酮的方法；以及制备沃格利波糖的方法。还提供了通过这些方法形成的化合物。
• METHOD FOR PRODUCING POLYHYDRIC PHENOL
  申请人：Kitagawa Hideo

  公开号：US20120046498A1

  公开（公告）日：2012-02-23

  The present invention is a method for producing a polyhydric phenol, including the following steps (a) to (d): (a) a first step of producing (4S,5R,6S)-4,5,6-trihydroxy-2-cyclohexcene- 1 -one from 2-deoxy-scyllo-inosose by a dehydration reaction; (b) a second step of producing 1,2,4-trihydroxybenzene from the (4S,5R,6S)-4,5,6-trihydroxy-2-cyclohexene- 1 -one obtained in the first step by a dehydration reaction; (c) a third step of producing 4-hydroxycyclohexane-1,3-dione from the 1,2,4-trihydroxybenzene by a catalytic hydrogenation reaction with the use of a metal catalyst; and (d) a fourth step of producing hydroquinone by heating the 4-hydroxycyclohexane-1,3-dione.

  本发明涉及一种生产多羟基苯酚的方法，包括以下步骤（a）至（d）：（a）第一步，通过脱水反应从2-去氧-赤藓糖生成（4S，5R，6S）-4,5,6-三羟基-2-环己烯-1-酮；（b）第二步，通过脱水反应从第一步得到的（4S，5R，6S）-4,5,6-三羟基-2-环己烯-1-酮生成1,2,4-三羟基苯；（c）第三步，使用金属催化剂进行催化氢化反应，从1,2,4-三羟基苯生成4-羟基环己烷-1,3-二酮；（d）第四步，通过加热4-羟基环己烷-1,3-二酮生成对苯二酚。
• METHOD FOR PRODUCING CATECHOL
  申请人：Suzuki Tsuneji

  公开号：US20110034735A1

  公开（公告）日：2011-02-10

  Provided is a method for producing catechol in a one-pot by reacting (4S,5R,6S)-4,5,6-trihydroxy-2-cyclohexene-1-one under hydrogen-reducing conditions while heating.

  提供了一种方法，通过在氢还原条件下加热反应(4S,5R,6S)-4,5,6-三羟基-2-环己烯-1-酮，以一锅法生产邻苯二酚。
• CATECHOL MANUFACTURING METHOD
  申请人：Mitsui Chemicals, Inc.

  公开号：EP2266940A1

  公开（公告）日：2010-12-29

  Provided is a method for producing catechol in a one-pot by reacting (4S,5R,6S)-4,5,6-trihydroxy-2-cyclohexene-1-one under hydrogen-reducing conditions while heating.

  本发明提供了一种在氢还原条件下加热反应 (4S,5R,6S)-4,5,6-三羟基-2-环己烯-1-酮的单锅生产邻苯二酚的方法。