Trehalose octaacetate | 25018-27-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Trehalose octaacetate
• 英文别名: [3,4,5-triacetyloxy-6-[3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxyoxan-2-yl]methyl acetate
• CAS: 25018-27-3
• 化学式: C₂₈H₃₈O₁₉
• 分子量: 678.6
• InChiKey: HWDSLHMSWAHPBA-UHFFFAOYSA-N

物化性质

• 熔点：
  96-98 °C
• 沸点：
  657.3±55.0 °C(Predicted)
• 密度：
  1.37±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  47
• 可旋转键数：
  20
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  238
• 氢给体数：
  0
• 氢受体数：
  19

文献信息

• Gel formulations for local drug release
  申请人：TECHNICAL UNIVERSITY OF DENMARK

  公开号：US11065201B2

  公开（公告）日：2021-07-20

  The present invention relates to a composition comprising non-water soluble carbohydrates, wherein at least 50% of the non-water soluble carbohydrates are carbohydrates selected from derivatives of lactose, maltose, trehalose, raffinose, glucosamine, galactosamine, lactosamine, or derivatives of disaccharides with at least two pyranose saccharide units, trisaccharides, tetrasaccharides, or mixtures thereof, and wherein the composition is a liquid before administration into the human or animal body and increases in viscosity by more than 1,000 centipoise (cP) after administration, for use as a medicament.

  本发明涉及一种包含非水溶性碳水化合物的组合物，其中至少50%的非水溶性碳水化合物是选自乳糖、麦芽糖、树海糖、棉子糖、葡糖胺、半乳糖胺、乳糖胺的衍生物、或具有至少两个吡喃糖糖单位的二糖、三糖、四糖或其混合物的衍生物，其中的组合物在注入人体或动物体内前为液体，在注入人体或动物体内后粘度增加超过 1,000 厘泊 (cP)，可用作药物。
• GEL FORMULATIONS FOR LOCAL DRUG RELEASE
  申请人：TECHNICAL UNIVERSITY OF DENMARK

  公开号：US20210386669A1

  公开（公告）日：2021-12-16

  The present invention relates to a composition comprising non-water soluble carbohydrates, wherein at least 50% of the non-water soluble carbohydrates are carbohydrates selected from derivatives of lactose, maltose, trehalose, raffinose, glucosamine, galactosamine, lactosamine, or derivatives of disaccharides with at least two pyranose saccharide units, trisaccharides, tetrasaccharides, or mixtures thereof, and wherein the composition is a liquid before administration into the human or animal body and increases in viscosity by more than 1,000 centipoise (cP) after administration, for use as a medicament.

表征谱图