BIIL-260-glucuronate | 204974-94-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: BIIL-260-glucuronate
• 英文别名: (2S,3S,4S,5R,6S)-6-[4-[2-[4-[[3-[(4-carbamimidoylphenoxy)methyl]phenyl]methoxy]phenyl]propan-2-yl]phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
• CAS: 204974-94-7
• 化学式: C₃₆H₃₈N₂O₉
• 分子量: 642.7
• InChiKey: FIMQVXNJBFDOAA-RSENBJTISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  47
• 可旋转键数：
  12
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  185
• 氢给体数：
  6
• 氢受体数：
  10

文献信息

• COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND PAIN USING A COMBINATION OF A COX-2 SELECTIVE INHIBITOR AND A LTB4 RECEPTOR ANTAGONIST
  申请人：Pharmacia Corporation

  公开号：EP1773396A1

  公开（公告）日：2007-04-18
• Compositions for the Treatment of Inflammation and Pain Using a Combination of a Cox-2 Selective Inhibitor and a Ltb4 Receptor Antagonist
  申请人：Patel Phenil Jayantilal

  公开号：US20080260817A1

  公开（公告）日：2008-10-23

  The present invention provides a therapeutic composition comprising a COX-2 selective inhibitor or a prodrug thereof and an LTB 4 receptor antagonist. A method is provided for the use of such composition in the treatment, prevention, or inhibition of inflammation, an inflammation-related disorder, pain, or a pain-related disorder.
• [EN] COMPOSITIONS FOR TREATMENT OF INFLAMMATION AND PAIN USING A COMBINATION OF A COX-2 SELECTIVE INHIBITOR AND A LTB4 RECEPTOR ANTAGONIST<br/>[FR] COMPOSITIONS POUR LE TRAITEMENT ANTI-INFLAMMATOIRE ET ANTI-DOULEUR AU MOYEN D'UNE COMBINAISON D'UN INHIBITEUR SELECTIF COX-2 ET D'UN ANTAGONISTE RECEPTEUR DE LTB4
  申请人：PHARMACIA CORP

  公开号：WO2006011048A1

  公开（公告）日：2006-02-02

  The present invention provides a therapeutic composition comprising a COX-2 selective inhibitor or a prodrug thereof and an LTB4 receptor antagonist. A method is provided for the use of such composition in the treatment, prevention, or inhibition of inflammation, an inflammation-related disorder, pain, or a pain-related disorder.