6-Hexadecanolactone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 6-Hexadecanolactone
• 英文别名: 7-decyloxepan-2-one
• 化学式: C₁₆H₃₀O₂
• 分子量: 254.41
• InChiKey: JDBCCUBGERLOBZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Olfactory adaption and cross-adapting agents to reduce the perception of body odors
  申请人：Symrise AG

  公开号：EP2581077A2

  公开（公告）日：2013-04-17

  Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants. Methods of making deodorant compositions are also provided wherein a cross-adapting agent, alone or in combination with other such agents, are included in an amount effective to reduce perception of malodor.

  公开的除臭剂组合物包含一种交叉适应剂，单独使用或与其他此类制剂结合使用，其用量可有效减少恶臭的感觉。此外，还公开了一种除臭剂组合物，其中包含一种交叉适应剂，单独使用或与其他此类制剂一起使用时，其用量可有效减少对不同性别体味的感知。这些方法的特点是通过施用除臭剂组合物来减少体味，其中该组合物包含一定量的交叉适应剂，可有效减少对这种气味的感知。其他方法的特点是阻断体味，包括施用除臭剂组合物，其中该组合物包含一定量的交叉适应剂，能有效占据气味受体位点，从而阻断该位点与其他气味剂的相互作用。此外，还提供了制作除臭剂组合物的方法，其中交叉适应剂单独或与其他此类制剂结合使用，其用量可有效减少恶臭的感觉。
• Process for the preparation of macrocyclic esters
  申请人：——

  公开号：US20020095045A1

  公开（公告）日：2002-07-18

  Macrocyclic ester compounds can be prepared from oligoesters by thermal cleavage in the presence of a thermostable benzene derivative.

  大环酯化合物可在一种热稳定性苯衍生物存在的情况下，通过热裂解从低聚酯制备而成。
• Olfactory adaptation and cross-adapting agents to reduce the perception of body odors
  申请人：——

  公开号：US20030152538A1

  公开（公告）日：2003-08-14

  Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of gender-specific malodor. The methods feature reducing perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to reduce perception of such odor. Other methods feature blocking perceived body odor comprising administering a deodorant composition wherein the composition comprises an amount of cross-adapting agent effective to occupy an odorant receptor site, thereby blocking interaction of the site with other odorants. Methods of making deodorant compositions are also provided wherein a cross-adapting agent, alone or in combination with other such agents, are included in an amount effective to reduce perception of malodor.

  公开的除臭剂组合物包含一种交叉适应剂，单独使用或与其他此类制剂结合使用，其用量可有效减少恶臭的感觉。此外，还公开了一种除臭剂组合物，其中包含一种交叉适应剂，单独使用或与其他此类制剂一起使用时，其用量可有效减少对不同性别体味的感知。这些方法的特点是通过施用除臭剂组合物来减少体味，其中该组合物包含一定量的交叉适应剂，可有效减少对这种气味的感知。其他方法的特点是阻断体味，包括施用除臭剂组合物，其中该组合物包含一定量的交叉适应剂，能有效占据气味受体位点，从而阻断该位点与其他气味剂的相互作用。此外，还提供了制作除臭剂组合物的方法，其中交叉适应剂单独或与其他此类制剂结合使用，其用量可有效减少恶臭的感觉。
• EP1474095A4
  申请人：——

  公开号：EP1474095A4

  公开（公告）日：2007-11-28
• OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS
  申请人：MONELL CHEMICAL SENSES CENTER

  公开号：EP1474095A1

  公开（公告）日：2004-11-10