N,N′-bis(3-hydroxypropyl)oxamide | 2463-34-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,N′-bis(3-hydroxypropyl)oxamide
• 英文别名: Oxalsaeure-bis-(3-hydroxy-propylamid)；N,N'-bis-(3-hydroxy-propyl)-oxalamide；N,N'-Bis-(3-hydroxy-propyl)-oxalamid；N.N'-Bis-(3-hydroxy-propyl)-oxamid；N,N'-bis(3-hydroxypropyl)oxamide；N,N'-bis(3-hydroxypropyl)ethanediamide
• CAS: 2463-34-5
• 化学式: C₈H₁₆N₂O₄
• mdl: MFCD01027335
• 分子量: 204.226
• InChiKey: JPCJYZZUEISJGO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  98.7
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N,N′-bis(3-hydroxypropyl)oxamide 在 硝酸 、 乙酸酐 作用下， 生成 N,N'--bis(3-nitratopropyl)oxamide
  参考文献：
  名称：

  393.季铵硝酸盐。第二部分 硝基烷基醚，胺，酰胺和氨基甲酸酯与叔胺和相关化合物的反应

  摘要：

  DOI：

  10.1039/jr9560002006
• 作为产物：
  描述：

  氰 、 3-氨基-1-丙醇 在 水 作用下， 生成 N,N′-bis(3-hydroxypropyl)oxamide
  参考文献：
  名称：

  Reaction of Cyanogen with Organic Compounds. XI. Amino Alcohols¹

  摘要：

  DOI：

  10.1021/jo01100a015

文献信息

• Chemical process for the preparation of oxamide derivatives and
  申请人：Enichem Anic S.p.A.

  公开号：US04978786A1

  公开（公告）日：1990-12-18

  A process is described for the preparation of oxamide derivatives wherein one or both --NH.sub.2 groups are replaced by primary or secondary amino groups, through reaction of oxamide with a suitably selected amine of formula RR.sup.1 NH wherein R represents a substituted straight or branched (C.sub.2 -C.sub.12)alkyl radical wherein the substituent(s) or at least one of the substituents is selected from the group consisting of hydroxy, amino, mono-substituted amino, and di-substituted amino, and R.sup.1 represents hydrogen or an optionally substituted (C.sub.1 -C.sub.6)alkyl radical; representative oxamide derivatives which can thus be obtained useful as corrosion inhibitors, intermediates for polymers, polymer stabilizers, and slow-release fertilizers, are also described.

  本文描述了一种制备氧化酰胺衍生物的过程，其中一个或两个-NH.sub.2基团被一种适当选择的公式RR.sup.1 NH的一级或二级氨基取代，通过氧化酰胺与适当选择的胺反应，其中R代表取代的直链或支链（C.sub.2-C.sub.12）烷基基团，其中取代基或至少一个取代基选自羟基，氨基，单取代氨基和二取代氨基的群；还描述了可以获得的代表性氧化酰胺衍生物，其可用作腐蚀抑制剂，聚合物中间体，聚合物稳定剂和缓释肥料。
• A LITHOGRAPHIC PRINTING PLATE PRECURSOR
  申请人：AGFA NV

  公开号：US20220009219A1

  公开（公告）日：2022-01-13

  A lithographic printing plate precursor including a photopolymerisable coating and an overcoat layer provided on top of said layer, characterized in that the overcoat layer includes a compound comprising at least one moiety having a structure according to Formula (I): (I).

  一种平版印刷版前体，包括光聚合涂层和覆盖在该层上方的覆盖层。其特征在于覆盖层包括至少一个具有式(I)结构的基团的化合物：(I)。
• Hindered phenolic oxamide compounds and stabilized compositions
  申请人：ICI Americas Inc.

  公开号：US04645853A1

  公开（公告）日：1987-02-24

  Novel hindered phenolic compounds derived from oxamides are disclosed which are useful as stabilizers of synthetic polymer resins.

  本发明揭示了从肟酰胺衍生的新型阻碍型酚类化合物，其作为合成聚合物树脂的稳定剂具有应用价值。
• Oxamide derivatives, their use in stabilizing organic materials and stabilized organic materials containing the said oxamide derivatives
  申请人：UNIROYAL, INC.

  公开号：EP0002616A1

  公开（公告）日：1979-06-27

  Novel N,N'-bis [(alkylhydroxyphenyl) alkanoyloxyhydrocarbyl] oxamides which can be prepared by reacting an alkylhydroxyphenylalkanoic acid, an ester or anhydride thereof or a corresponding acid halide with an N,N'- bis(hydroxyhydrocarbyl) oxamide, are useful as stabilizers of organic materials normally subject to oxidative deterioration, e.g. polymers such as polyolefins. Methods of stabilizing organic materials subject to oxidative deterioration and stabilized organic materials with N,N'-bis [alkylhydroxyphenyl) alkanoyloxyhydrocarbyl] oxamides are provided.

  新型 N，N'-双[(烷基羟基苯基)烷酰氧基羟基羰基]草酰胺可通过烷基羟基苯基烷酸、其酯或酸酐或相应的酸卤化物与 N，N'-双(羟基羟基羰基)草酰胺反应制备，可用作通常会氧化变质的有机材料的稳定剂，例如聚烯烃等聚合物。本发明提供了稳定受氧化劣化影响的有机材料的方法以及用 N,N'-双[烷基羟基苯基] 烷酰氧基羟基羰基]草酰胺稳定有机材料的方法。
• A lithographic printing plate precursor and monomer
  申请人：AGFA GRAPHICS NV

  公开号：EP2883699A1

  公开（公告）日：2015-06-17

  A lithographic printing plate precursor is disclosed including (i) a support having a hydrophilic surface or which is provided with a hydrophilic layer, and (ii) a coating including a photopolymerisable layer, characterised in that the photopolymerisable layer comprises a compound comprising at least one moiety having a structure according to Formula (I): wherein X represents O or NR* and R* represents hydrogen, an optionally substituted alkyl, aryl, aralkyl or heteroaryl group; and * denotes the linking positions to the rest of the compound. The application further discloses a monomer including at least one moiety having a structure according to Formula (I) and at least one moiety having a structure according to Formula (VIII): wherein X represents O or NR* and wherein R* represents hydrogen, or an optionally substituted alkyl, aryl, aralkyl or heteroaryl group; R5 represents hydrogen or an optionally substituted alkyl group; and * denotes the linking positions to the rest of the monomer.

  本发明公开了一种平版印刷板前体，包括：(i) 具有亲水性表面或提供亲水层的支撑物；(ii) 包括可光聚合层的涂层、 其特征在于，可光聚合层包括一种化合物，该化合物至少包含一个具有式 (I) 结构的分子： 其中 X 代表 O 或 NR*，R* 代表氢、任选取代的烷基、芳基、芳烷基或杂芳基；以及 * 表示与化合物其余部分的连接位置。 该申请进一步公开了一种单体，包括至少一个具有式（I）结构的分子和至少一个具有式（VIII）结构的分子： 其中 X 代表 O 或 NR*，R* 代表氢或任选取代的烷基、芳基、芳烷基或杂芳基；R5 代表氢或任选取代的烷基；* 表示与单体其余部分的连接位置。