dorsmanin E

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: dorsmanin E
• 英文别名: 2',3'-h]Chromen-4-one；4-(3,4-dihydroxyphenyl)-10,10,16,16-tetramethyl-3,9,15-trioxatetracyclo[12.4.0.02,7.08,13]octadeca-1(14),2(7),8(13)-trien-6-one
• 化学式: C₂₅H₂₈O₆
• 分子量: 424.494
• InChiKey: JZNUJZPOJAHBOH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  31
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  85.2
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  6,8-diprenyleriodictyol 在 盐酸 作用下， 以 甲醇 为溶剂， 反应 2.0h， 以20 mg的产率得到dorsmanin E
  参考文献：
  名称：

  Prenylated flavanones from the twigs of Dorstenia mannii

  摘要：

  Investigation of the twigs of Dorstenia mannii gave 6,8-diprenyl-5,7,3'4'-tetrahydroxyflavanone and four new prenylated flavanones, named dorsmanins E-H and characterized as 5,6-7,8-bis-(2,2-dimethylchromano)-3',4'-dihydroxyflavanone, 7,8-[2 "-(1-hydroxy-1-methylethyl)-dihydrofurano]-6-prenyl-5,3',4'-trihydroxyflavanone, 6,7-[2 "-(1-hydroxy-1-methylethyl)dihydrofurano]-8-prenyl-5,3',4'-trihydroxyflavanone and 6-prenyl-8-(2-hydroxy-3-methylbut-3-enyl)-5,7,3',4'-tetrahydroxyflavanone, respectively, on the basis of spectral analysis and chemical evidence for the chromano derivative. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(98)00324-0

文献信息

• Prenylated flavanones from the twigs of Dorstenia mannii
  作者：Bonaventure T Ngadjui、Etienne Dongo、Helene Tamboue、Kouam Fogue、Berhanu M Abegaz

  DOI：10.1016/s0031-9422(98)00324-0

  日期：1999.4

  Investigation of the twigs of Dorstenia mannii gave 6,8-diprenyl-5,7,3'4'-tetrahydroxyflavanone and four new prenylated flavanones, named dorsmanins E-H and characterized as 5,6-7,8-bis-(2,2-dimethylchromano)-3',4'-dihydroxyflavanone, 7,8-[2 "-(1-hydroxy-1-methylethyl)-dihydrofurano]-6-prenyl-5,3',4'-trihydroxyflavanone, 6,7-[2 "-(1-hydroxy-1-methylethyl)dihydrofurano]-8-prenyl-5,3',4'-trihydroxyflavanone and 6-prenyl-8-(2-hydroxy-3-methylbut-3-enyl)-5,7,3',4'-tetrahydroxyflavanone, respectively, on the basis of spectral analysis and chemical evidence for the chromano derivative. (C) 1999 Elsevier Science Ltd. All rights reserved.